Mounting of Biomaterials for Use in Ophthalmic Cell Therapies
When used as scaffolds for cell therapies, biomaterials often present basic handling and logistical problems for scientists and surgeons alike. The quest for an appropriate mounting device for biomaterials is therefore a significant and common problem. In this review, we provide a detailed overview...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2017-11-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.1177/0963689717723638 |
| _version_ | 1818519980757483520 |
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| author | Damien G. Harkin Siobhan E. Dunphy Audra M. A. Shadforth Rebecca A. Dawson Jennifer Walshe Nadia Zakaria |
| author_facet | Damien G. Harkin Siobhan E. Dunphy Audra M. A. Shadforth Rebecca A. Dawson Jennifer Walshe Nadia Zakaria |
| author_sort | Damien G. Harkin |
| collection | DOAJ |
| description | When used as scaffolds for cell therapies, biomaterials often present basic handling and logistical problems for scientists and surgeons alike. The quest for an appropriate mounting device for biomaterials is therefore a significant and common problem. In this review, we provide a detailed overview of the factors to consider when choosing an appropriate mounting device including those experienced during cell culture, quality assurance, and surgery. By way of example, we draw upon our combined experience in developing epithelial cell therapies for the treatment of eye diseases. We discuss commercially available options for achieving required goals and provide a detailed analysis of 4 experimental designs developed within our respective laboratories in Australia, the United Kingdom, and Belgium. |
| first_indexed | 2024-12-11T01:31:17Z |
| format | Article |
| id | doaj.art-ff6ae815c00840b69616bdf294a54143 |
| institution | Directory Open Access Journal |
| issn | 0963-6897 1555-3892 |
| language | English |
| last_indexed | 2024-12-11T01:31:17Z |
| publishDate | 2017-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Cell Transplantation |
| spelling | doaj.art-ff6ae815c00840b69616bdf294a541432022-12-22T01:25:22ZengSAGE PublishingCell Transplantation0963-68971555-38922017-11-012610.1177/0963689717723638Mounting of Biomaterials for Use in Ophthalmic Cell TherapiesDamien G. Harkin0Siobhan E. Dunphy1Audra M. A. Shadforth2Rebecca A. Dawson3Jennifer Walshe4Nadia Zakaria5 Queensland Eye Institute, South Brisbane, Queensland, Australia Department of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College, Dublin, Ireland Queensland Eye Institute, South Brisbane, Queensland, Australia Queensland Eye Institute, South Brisbane, Queensland, Australia Queensland Eye Institute, South Brisbane, Queensland, Australia Department of Ophthalmology, Visual Optics and Visual Rehabilitation, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, BelgiumWhen used as scaffolds for cell therapies, biomaterials often present basic handling and logistical problems for scientists and surgeons alike. The quest for an appropriate mounting device for biomaterials is therefore a significant and common problem. In this review, we provide a detailed overview of the factors to consider when choosing an appropriate mounting device including those experienced during cell culture, quality assurance, and surgery. By way of example, we draw upon our combined experience in developing epithelial cell therapies for the treatment of eye diseases. We discuss commercially available options for achieving required goals and provide a detailed analysis of 4 experimental designs developed within our respective laboratories in Australia, the United Kingdom, and Belgium.https://doi.org/10.1177/0963689717723638 |
| spellingShingle | Damien G. Harkin Siobhan E. Dunphy Audra M. A. Shadforth Rebecca A. Dawson Jennifer Walshe Nadia Zakaria Mounting of Biomaterials for Use in Ophthalmic Cell Therapies Cell Transplantation |
| title | Mounting of Biomaterials for Use in Ophthalmic Cell Therapies |
| title_full | Mounting of Biomaterials for Use in Ophthalmic Cell Therapies |
| title_fullStr | Mounting of Biomaterials for Use in Ophthalmic Cell Therapies |
| title_full_unstemmed | Mounting of Biomaterials for Use in Ophthalmic Cell Therapies |
| title_short | Mounting of Biomaterials for Use in Ophthalmic Cell Therapies |
| title_sort | mounting of biomaterials for use in ophthalmic cell therapies |
| url | https://doi.org/10.1177/0963689717723638 |
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