Mucormycosis and acute kidney injury
Mucormycosis, although said to be less common than candidiasis and aspergillosis is becoming increasingly associated with many co-morbid conditions and immunosuppression. Renal involvement, rarely reported previously, has also been documented with increasing frequency in recent times in both disease...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Society of Diabetic Nephropathy Prevention
2012-10-01
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| Series: | Journal of Nephropathology |
| Subjects: | |
| Online Access: | https://nephropathol.com/PDF/JNP-1-155.pdf |
| _version_ | 1797827951574646784 |
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| author | Krishan L Gupta Aakriti Gupta |
| author_facet | Krishan L Gupta Aakriti Gupta |
| author_sort | Krishan L Gupta |
| collection | DOAJ |
| description | Mucormycosis, although said to be less common than candidiasis and aspergillosis is becoming increasingly associated with many co-morbid conditions and immunosuppression. Renal involvement, rarely reported previously, has also been documented with increasing frequency in recent times in both diseased as well as apparently healthy individuals. The kidneys may be involved in disseminated disease or have an isolated involvement for unexplained reasons. The manifestations are very serious particularly in patients with bilateral renal mucormycosis who often develop acute kidney injury and usually have a fatal outcome. The diagnosis of the renal mucormycosis is based on renal histology sections of renal biopsy or nephrectomised kidneys. Imaging with computerised tomography with contrast is of tremendous help in early identification of these cases before histological diagnosis. Once diagnosis is established, prompt treatment with antifungal medication, including Amphotericin-B (and its lipid formulations) and posaconazole, and removal of infected tissue is necessary to save from otherwise fatal infection. |
| first_indexed | 2024-04-09T12:56:39Z |
| format | Article |
| id | doaj.art-ff6bf5fb93d2427ead050243d6ee1460 |
| institution | Directory Open Access Journal |
| issn | 2251-8363 2251-8819 |
| language | English |
| last_indexed | 2024-04-09T12:56:39Z |
| publishDate | 2012-10-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Nephropathology |
| spelling | doaj.art-ff6bf5fb93d2427ead050243d6ee14602023-05-13T11:44:12ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropathology2251-83632251-88192012-10-011315515910.5812/nephropathol.8111JNP_20130220165938Mucormycosis and acute kidney injuryKrishan L Gupta0Aakriti Gupta1Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.Yale University School of Medicine, New Haven CT, USA.Mucormycosis, although said to be less common than candidiasis and aspergillosis is becoming increasingly associated with many co-morbid conditions and immunosuppression. Renal involvement, rarely reported previously, has also been documented with increasing frequency in recent times in both diseased as well as apparently healthy individuals. The kidneys may be involved in disseminated disease or have an isolated involvement for unexplained reasons. The manifestations are very serious particularly in patients with bilateral renal mucormycosis who often develop acute kidney injury and usually have a fatal outcome. The diagnosis of the renal mucormycosis is based on renal histology sections of renal biopsy or nephrectomised kidneys. Imaging with computerised tomography with contrast is of tremendous help in early identification of these cases before histological diagnosis. Once diagnosis is established, prompt treatment with antifungal medication, including Amphotericin-B (and its lipid formulations) and posaconazole, and removal of infected tissue is necessary to save from otherwise fatal infection.https://nephropathol.com/PDF/JNP-1-155.pdfmucoralesrenal mucormycosisacute kidney injury |
| spellingShingle | Krishan L Gupta Aakriti Gupta Mucormycosis and acute kidney injury Journal of Nephropathology mucorales renal mucormycosis acute kidney injury |
| title | Mucormycosis and acute kidney injury |
| title_full | Mucormycosis and acute kidney injury |
| title_fullStr | Mucormycosis and acute kidney injury |
| title_full_unstemmed | Mucormycosis and acute kidney injury |
| title_short | Mucormycosis and acute kidney injury |
| title_sort | mucormycosis and acute kidney injury |
| topic | mucorales renal mucormycosis acute kidney injury |
| url | https://nephropathol.com/PDF/JNP-1-155.pdf |
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