Idiopathic pulmonary hemosiderosis in a 9-year-old girl
<p>Abstract</p> <p>Diffuse alveolar hemorrhage (DAH) is a rare and life-threatening condition characterized by hemoptysis, dyspnoea, alveolar infiltrates on chest radiograph and various degrees of anemia. It may occur either as a primary disease of the lungs or a secondary conditio...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2009-12-01
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| Series: | European Journal of Medical Research |
| Subjects: | |
| Online Access: | http://www.eurjmedres.com/content/14/S4/112 |
| _version_ | 1818358851579150336 |
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| author | Kamienska E Urasinski T Gawlikowska-Sroka A Glura B Pogorzelski A |
| author_facet | Kamienska E Urasinski T Gawlikowska-Sroka A Glura B Pogorzelski A |
| author_sort | Kamienska E |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Diffuse alveolar hemorrhage (DAH) is a rare and life-threatening condition characterized by hemoptysis, dyspnoea, alveolar infiltrates on chest radiograph and various degrees of anemia. It may occur either as a primary disease of the lungs or a secondary condition due to cardiac, systemic vascular, collagen or renal diseases. Idiopathic pulmonary hemosiderosis (IPH) is a separate form of DAH of unknown origin, associated in some cases with celiac disease. The estimated incidence of IPH in children is 0.24-1.23 cases per million, with a mortality rate as high as 50%. Only about 500 cases of this disease have been described in medical literature. We present a case of a 9-year-old girl diagnosed with IPH, which was confirmed by the presence of many hemosiderin-laden macrophages in bronchoalveolar lavage obtained by bronchofiberoscopy. Therapy with glucocorticoids was initiated with a partial and transient response. Azathioprine and a gluten-free diet were subsequently introduced. However, the girl still suffers from recurrent episodes of hemoptysis, dyspnea and anemia.</p> |
| first_indexed | 2024-12-13T20:35:34Z |
| format | Article |
| id | doaj.art-ff70d6301c384ea3956c2f1d840083fa |
| institution | Directory Open Access Journal |
| issn | 2047-783X |
| language | English |
| last_indexed | 2024-12-13T20:35:34Z |
| publishDate | 2009-12-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj.art-ff70d6301c384ea3956c2f1d840083fa2022-12-21T23:32:18ZengBMCEuropean Journal of Medical Research2047-783X2009-12-0114Suppl 411211510.1186/2047-783X-14-S4-112Idiopathic pulmonary hemosiderosis in a 9-year-old girlKamienska EUrasinski TGawlikowska-Sroka AGlura BPogorzelski A<p>Abstract</p> <p>Diffuse alveolar hemorrhage (DAH) is a rare and life-threatening condition characterized by hemoptysis, dyspnoea, alveolar infiltrates on chest radiograph and various degrees of anemia. It may occur either as a primary disease of the lungs or a secondary condition due to cardiac, systemic vascular, collagen or renal diseases. Idiopathic pulmonary hemosiderosis (IPH) is a separate form of DAH of unknown origin, associated in some cases with celiac disease. The estimated incidence of IPH in children is 0.24-1.23 cases per million, with a mortality rate as high as 50%. Only about 500 cases of this disease have been described in medical literature. We present a case of a 9-year-old girl diagnosed with IPH, which was confirmed by the presence of many hemosiderin-laden macrophages in bronchoalveolar lavage obtained by bronchofiberoscopy. Therapy with glucocorticoids was initiated with a partial and transient response. Azathioprine and a gluten-free diet were subsequently introduced. However, the girl still suffers from recurrent episodes of hemoptysis, dyspnea and anemia.</p>http://www.eurjmedres.com/content/14/S4/112diffuse alveolarhemoptysishemorrhagehemosiderosisidiopathic pulmonary |
| spellingShingle | Kamienska E Urasinski T Gawlikowska-Sroka A Glura B Pogorzelski A Idiopathic pulmonary hemosiderosis in a 9-year-old girl European Journal of Medical Research diffuse alveolar hemoptysis hemorrhage hemosiderosis idiopathic pulmonary |
| title | Idiopathic pulmonary hemosiderosis in a 9-year-old girl |
| title_full | Idiopathic pulmonary hemosiderosis in a 9-year-old girl |
| title_fullStr | Idiopathic pulmonary hemosiderosis in a 9-year-old girl |
| title_full_unstemmed | Idiopathic pulmonary hemosiderosis in a 9-year-old girl |
| title_short | Idiopathic pulmonary hemosiderosis in a 9-year-old girl |
| title_sort | idiopathic pulmonary hemosiderosis in a 9 year old girl |
| topic | diffuse alveolar hemoptysis hemorrhage hemosiderosis idiopathic pulmonary |
| url | http://www.eurjmedres.com/content/14/S4/112 |
| work_keys_str_mv | AT kamienskae idiopathicpulmonaryhemosiderosisina9yearoldgirl AT urasinskit idiopathicpulmonaryhemosiderosisina9yearoldgirl AT gawlikowskasrokaa idiopathicpulmonaryhemosiderosisina9yearoldgirl AT glurab idiopathicpulmonaryhemosiderosisina9yearoldgirl AT pogorzelskia idiopathicpulmonaryhemosiderosisina9yearoldgirl |