Lymphomas of the gastro-intestinal tract - Pathophysiology, pathology, and differential diagnosis
The gastrointestinal tract (GIT) is the most commonly involved site of extranodal lymphomas. The close association between chronic inflammation and specific GIT lymphomas not only provide interesting insights into the pathobiology of lymphomas but also poses unique diagnostic challenges. A clear und...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=1;spage=1;epage=16;aulast=Cardona |
| _version_ | 1818961168081879040 |
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| author | Diana M Cardona Amanda Layne Anand S Lagoo |
| author_facet | Diana M Cardona Amanda Layne Anand S Lagoo |
| author_sort | Diana M Cardona |
| collection | DOAJ |
| description | The gastrointestinal tract (GIT) is the most commonly involved site of extranodal lymphomas. The close association between chronic inflammation and specific GIT lymphomas not only provide interesting insights into the pathobiology of lymphomas but also poses unique diagnostic challenges. A clear understanding of marginal zone and mucosa associated lymphoid tissue (MALT) in health and disease is helpful to place GIT lymphomas in proper context. A wide variety of lymphomas besides MALT lymphomas occur in various parts of the GIT. The characteristic pathological, immunophenotypic, and genetic features of different GIT lymphomas categorized according to World Health Organization (WHO) classification are presented. The epidemiological, clinical, and pathological features of lymphomas occurring in each part of the GIT are summarized and the key points regarding lymphomas at each site are emphasized. A tabular summary of the important differential diagnostic considerations at each site is given and suggestions for a minimal diagnostic work up are provided. |
| first_indexed | 2024-12-20T12:09:08Z |
| format | Article |
| id | doaj.art-ff7185c346c24f1ea15ba3ba187a5bc5 |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-12-20T12:09:08Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-ff7185c346c24f1ea15ba3ba187a5bc52022-12-21T19:41:17ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292012-01-0155111610.4103/0377-4929.94847Lymphomas of the gastro-intestinal tract - Pathophysiology, pathology, and differential diagnosisDiana M CardonaAmanda LayneAnand S LagooThe gastrointestinal tract (GIT) is the most commonly involved site of extranodal lymphomas. The close association between chronic inflammation and specific GIT lymphomas not only provide interesting insights into the pathobiology of lymphomas but also poses unique diagnostic challenges. A clear understanding of marginal zone and mucosa associated lymphoid tissue (MALT) in health and disease is helpful to place GIT lymphomas in proper context. A wide variety of lymphomas besides MALT lymphomas occur in various parts of the GIT. The characteristic pathological, immunophenotypic, and genetic features of different GIT lymphomas categorized according to World Health Organization (WHO) classification are presented. The epidemiological, clinical, and pathological features of lymphomas occurring in each part of the GIT are summarized and the key points regarding lymphomas at each site are emphasized. A tabular summary of the important differential diagnostic considerations at each site is given and suggestions for a minimal diagnostic work up are provided.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=1;spage=1;epage=16;aulast=CardonaCeliac diseaseextra-nodalgastro-intestinallymphomamucosa associated lymphoid tissue |
| spellingShingle | Diana M Cardona Amanda Layne Anand S Lagoo Lymphomas of the gastro-intestinal tract - Pathophysiology, pathology, and differential diagnosis Indian Journal of Pathology and Microbiology Celiac disease extra-nodal gastro-intestinal lymphoma mucosa associated lymphoid tissue |
| title | Lymphomas of the gastro-intestinal tract - Pathophysiology, pathology, and differential diagnosis |
| title_full | Lymphomas of the gastro-intestinal tract - Pathophysiology, pathology, and differential diagnosis |
| title_fullStr | Lymphomas of the gastro-intestinal tract - Pathophysiology, pathology, and differential diagnosis |
| title_full_unstemmed | Lymphomas of the gastro-intestinal tract - Pathophysiology, pathology, and differential diagnosis |
| title_short | Lymphomas of the gastro-intestinal tract - Pathophysiology, pathology, and differential diagnosis |
| title_sort | lymphomas of the gastro intestinal tract pathophysiology pathology and differential diagnosis |
| topic | Celiac disease extra-nodal gastro-intestinal lymphoma mucosa associated lymphoid tissue |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=1;spage=1;epage=16;aulast=Cardona |
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