The geriatric nutritional risk index is an effective tool to detect GLIM-defined malnutrition in rectal cancer patients
BackgroundThis study aimed to investigate the value of the Geriatric Nutritional Risk Index (GNRI), prognostic nutritional index (PNI), and advanced lung cancer inflammation index (ALI) scores in detecting malnutrition in patients with rectal cancer; the Global Leadership Initiative on Malnutrition...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.1061944/full |
| _version_ | 1828292210946211840 |
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| author | Xi-Yi Chen Yi Lin Shang-Yu Yin Ya-Ting Shen Xi-Cheng Zhang Ke-Ke Chen Chong-Jun Zhou Chen-Guo Zheng |
| author_facet | Xi-Yi Chen Yi Lin Shang-Yu Yin Ya-Ting Shen Xi-Cheng Zhang Ke-Ke Chen Chong-Jun Zhou Chen-Guo Zheng |
| author_sort | Xi-Yi Chen |
| collection | DOAJ |
| description | BackgroundThis study aimed to investigate the value of the Geriatric Nutritional Risk Index (GNRI), prognostic nutritional index (PNI), and advanced lung cancer inflammation index (ALI) scores in detecting malnutrition in patients with rectal cancer; the Global Leadership Initiative on Malnutrition (GLIM) was used as the reference criterion.Materials and methodsThis study included patients with rectal cancer who underwent proctectomy. GNRI, PNI, and ALI were calculated to detect the GLIM-defined malnutrition using the Receiver operating characteristic (ROC) curves. Univariate and multivariate logistic regression analyses were used to evaluate the association between the nutritional tools and postoperative complications. Kaplan-Meier survival curves, log-rank tests, and univariate and multivariate Cox regression analyses were used to clarify the relationship between nutritional tools and overall survival (OS).ResultsThis study enrolled 636 patients with rectal cancer. The GNRI demonstrated the highest sensitivity (77.8%), pretty specificity (69.0%), and the largest AUC (0.734). The GNRI showed good property in predicting major postoperative complications. All three nutritional tools were independent predictors of OS.ConclusionThe GNRI can be used as a promising alternative to the GLIM and is optimal in perioperative management of patients with rectal cancer. |
| first_indexed | 2024-04-13T11:05:03Z |
| format | Article |
| id | doaj.art-ff7547f3e25245e68d95aeb5a84cdeb4 |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-04-13T11:05:03Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-ff7547f3e25245e68d95aeb5a84cdeb42022-12-22T02:49:18ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-11-01910.3389/fnut.2022.10619441061944The geriatric nutritional risk index is an effective tool to detect GLIM-defined malnutrition in rectal cancer patientsXi-Yi Chen0Yi Lin1Shang-Yu Yin2Ya-Ting Shen3Xi-Cheng Zhang4Ke-Ke Chen5Chong-Jun Zhou6Chen-Guo Zheng7Department of Cardiovascular and Thoracic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Endocrinology, The Third Affiliated Hospital of Shanghai University, The Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, ChinaDepartment of Anorectal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Anorectal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Anorectal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Anorectal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Anorectal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Anorectal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, ChinaBackgroundThis study aimed to investigate the value of the Geriatric Nutritional Risk Index (GNRI), prognostic nutritional index (PNI), and advanced lung cancer inflammation index (ALI) scores in detecting malnutrition in patients with rectal cancer; the Global Leadership Initiative on Malnutrition (GLIM) was used as the reference criterion.Materials and methodsThis study included patients with rectal cancer who underwent proctectomy. GNRI, PNI, and ALI were calculated to detect the GLIM-defined malnutrition using the Receiver operating characteristic (ROC) curves. Univariate and multivariate logistic regression analyses were used to evaluate the association between the nutritional tools and postoperative complications. Kaplan-Meier survival curves, log-rank tests, and univariate and multivariate Cox regression analyses were used to clarify the relationship between nutritional tools and overall survival (OS).ResultsThis study enrolled 636 patients with rectal cancer. The GNRI demonstrated the highest sensitivity (77.8%), pretty specificity (69.0%), and the largest AUC (0.734). The GNRI showed good property in predicting major postoperative complications. All three nutritional tools were independent predictors of OS.ConclusionThe GNRI can be used as a promising alternative to the GLIM and is optimal in perioperative management of patients with rectal cancer.https://www.frontiersin.org/articles/10.3389/fnut.2022.1061944/fullGLIMGNRIPNIALImalnutritionrectal cancer |
| spellingShingle | Xi-Yi Chen Yi Lin Shang-Yu Yin Ya-Ting Shen Xi-Cheng Zhang Ke-Ke Chen Chong-Jun Zhou Chen-Guo Zheng The geriatric nutritional risk index is an effective tool to detect GLIM-defined malnutrition in rectal cancer patients Frontiers in Nutrition GLIM GNRI PNI ALI malnutrition rectal cancer |
| title | The geriatric nutritional risk index is an effective tool to detect GLIM-defined malnutrition in rectal cancer patients |
| title_full | The geriatric nutritional risk index is an effective tool to detect GLIM-defined malnutrition in rectal cancer patients |
| title_fullStr | The geriatric nutritional risk index is an effective tool to detect GLIM-defined malnutrition in rectal cancer patients |
| title_full_unstemmed | The geriatric nutritional risk index is an effective tool to detect GLIM-defined malnutrition in rectal cancer patients |
| title_short | The geriatric nutritional risk index is an effective tool to detect GLIM-defined malnutrition in rectal cancer patients |
| title_sort | geriatric nutritional risk index is an effective tool to detect glim defined malnutrition in rectal cancer patients |
| topic | GLIM GNRI PNI ALI malnutrition rectal cancer |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2022.1061944/full |
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