TARSII and CARSII: Two approaches for SNP-independent identification of germline differentially methylated regions in mammals

Summary: Identifying germline differentially methylated regions (DMRs) in outbred mammals remains a challenge because of difficulty in obtaining single-nucleotide polymorphisms (SNPs). To overcome this difficulty, we developed two computational approaches, TARSII and CARSII, which allow accurate pre...

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Bibliographic Details
Main Authors: Wenhao Zhang, Yi Zhang
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722001204