A Mixture of Endocrine Disrupting Chemicals Associated with Lower Birth Weight in Children Induces Adipogenesis and DNA Methylation Changes in Human Mesenchymal Stem Cells

A Mixture of Endocrine Disrupting Chemicals Associated with Lower Birth Weight in Children Induces Adipogenesis and DNA Methylation Changes in Human Mesenchymal Stem Cells

Endocrine Disrupting Chemicals (EDCs) are man-made compounds that alter functions of the endocrine system. Environmental mixtures of EDCs might have adverse effects on human health, even though their individual concentrations are below regulatory levels of concerns. However, studies identifying and...

Full description

Bibliographic Details
Main Authors:	Polina Lizunkova, Elin Engdahl, Gábor Borbély, Chris Gennings, Christian Lindh, Carl-Gustaf Bornehag, Joëlle Rüegg
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	International Journal of Molecular Sciences
Subjects:	Endocrine Disrupting Chemicals EDC chemical mixtures mesenchymal stem cells adipogenesis DNA methylation
Online Access:	https://www.mdpi.com/1422-0067/23/4/2320

Similar Items

Prenatal exposures to mixtures of endocrine disrupting chemicals and sex-specific associations with children’s BMI and overweight at 5.5 years of age in the SELMA study
by: Katherine Svensson, et al.
Published: (2023-09-01)

BPA, BPAF and TMBPF Alter Adipogenesis and Fat Accumulation in Human Mesenchymal Stem Cells, with Implications for Obesity
by: Isabel C. Cohen, et al.
Published: (2021-05-01)

From Cohort to Cohort: A Similar Mixture Approach (SMACH) to Evaluate Exposures to a Mixture Leading to Thyroid-Mediated Neurodevelopmental Effects Using NHANES Data
by: Maria Sapounidou, et al.
Published: (2023-03-01)

Endocrine-active and endocrine-disrupting compounds in food – occurrence, formation and relevance
by: Constanze Stiefel, et al.
Published: (2023-06-01)

Endocrine-Disrupting Chemicals and Their Effects in Pet Dogs and Cats: An Overview
by: Paola Pocar, et al.
Published: (2023-01-01)

Expression, secretion and functional characterization of three laccases in E. coli
by: Yating Mo, et al.
Published: (2022-03-01)

Effects of Diethylstilbestrol on Zebrafish Gonad Development and Endocrine Disruption Mechanism
by: Xuan Liu, et al.
Published: (2021-06-01)

Endocrine Disrupting Chemicals: An Occult Mediator of Metabolic Disease
by: Olga Papalou, et al.
Published: (2019-03-01)

Association of endocrine disrupting chemicals exposure with human chorionic gonadotropin concentrations in pregnancy
by: Arash Derakhshan, et al.
Published: (2023-08-01)

Cetyl Alcohol Polyethoxylates Disrupt Metabolic Health in Developmentally Exposed Zebrafish
by: Matthew K. LeFauve, et al.
Published: (2023-02-01)

Perinatal Exposure to Phthalates: From Endocrine to Neurodevelopment Effects
by: Laura Lucaccioni, et al.
Published: (2021-04-01)

Uncovering Evidence for Endocrine-Disrupting Chemicals That Elicit Differential Susceptibility through Gene-Environment Interactions
by: Dylan J. Wallis, et al.
Published: (2021-04-01)

Rejection of endocrine disruption chemical (EDU) using nanofiltration /
by: Mohd. Razman Salim 376503, et al.
Published: (2008)

The Potential Relationship Between Environmental Endocrine Disruptor Exposure and the Development of Endometriosis and Adenomyosis
by: Victoria R. Stephens, et al.
Published: (2022-01-01)

Corrigendum: The potential relationship between environmental endocrine disruptor exposure and the development of endometriosis and adenomyosis
by: Victoria R. Stephens, et al.
Published: (2023-08-01)

Prenatal Exposure to an EDC Mixture, NeuroMix: Effects on Brain, Behavior, and Stress Responsiveness in Rats
by: Andrea C. Gore, et al.
Published: (2022-03-01)

EDCs Mixtures: A Stealthy Hazard for Human Health?
by: Edna Ribeiro, et al.
Published: (2017-02-01)

Diurnal Variation in Biomarkers of Exposure to Endocrine-Disrupting Chemicals and Their Association with Oxidative Damage in Norwegian Adults: The EuroMix Study
by: Samuel Olushola Abimbola, et al.
Published: (2022-04-01)

Early-life exposure to endocrine-disrupting chemicals and autistic traits in childhood and adolescence: a systematic review of epidemiological studies
by: Yandra Giovanna de Oliveira Cunha, et al.
Published: (2023-06-01)

Fetal–Maternal Exposure to Endocrine Disruptors: Correlation with Diet Intake and Pregnancy Outcomes
by: Alessandro Rolfo, et al.
Published: (2020-06-01)

The ENDpoiNTs Project: Novel Testing Strategies for Endocrine Disruptors Linked to Developmental Neurotoxicity
by: Diana Lupu, et al.
Published: (2020-06-01)

Endocrine-Disrupting Chemicals and Disease Endpoints
by: Changhwan Ahn, et al.
Published: (2023-03-01)

Application of In Vitro Models for Studying the Mechanisms Underlying the Obesogenic Action of Endocrine-Disrupting Chemicals (EDCs) as Food Contaminants—A Review
by: Monika Kowalczyk, et al.
Published: (2023-01-01)

Identification of endocrine-disrupting chemicals targeting key DCM-associated genes via bioinformatics and machine learning
by: Shu Li, et al.
Published: (2024-04-01)

Endocrine-Disrupting Chemicals and Insulin Resistance in Children
by: Eleonora Rotondo, et al.
Published: (2020-05-01)

Dietary Intake of Endocrine Disrupting Substances Presents in Environment and Their Impact on Thyroid Function
by: Aneta Sokal, et al.
Published: (2021-03-01)

Perinatal exposure to the fungicide ketoconazole alters hypothalamic control of puberty in female rats
by: Delphine Franssen, et al.
Published: (2023-04-01)

Nonylphenol Polyethoxylates Enhance Adipose Deposition in Developmentally Exposed Zebrafish
by: Christopher D. Kassotis, et al.
Published: (2022-02-01)

Investigation on impact of endocrine disrupting compounds (EDCs) in aquatic environment /
by: Lee, Kah Khim, 1991-, author, et al.
Published: (2015)

Editorial: Endocrine disruptors and diseases of brain and mind: past and prelude
by: Ashu Johri, et al.
Published: (2024-01-01)

Investigation on impact of endocrine disrupting compounds (EDCs) in aquatic environment [electronic resource] /
by: Lee, Kah Khim, 1991-, author
Published: (2015)

Pharmaceuticals, personal care products and endocrine disrupting agents in the environment-a review/
by: 495818 Caliman, Florentina Anca, et al.

Editorial: Pharmaceuticals, personal care products and endocrine disrupting chemicals: The physiological consequences of exposure to pollutants in aquatic animals
by: Mingzhe Yuan, et al.
Published: (2023-01-01)

Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting
by: Maria Elisabeth Street, et al.
Published: (2018-06-01)

Aptamer-Based Biosensors for the Analytical Determination of Bisphenol A in Foodstuffs
by: Marica Erminia Schiano, et al.
Published: (2022-04-01)

Pet cats, the better sentinels for indoor organic pollutants
by: Tingting Ma, et al.
Published: (2022-10-01)

Endocrine disruption modeling /
by: Devillers, J. (James), 1956-
Published: (c200)

Mechanism of action of triclosan as an endocrine-disrupting chemical with its impact on human health – literature review
by: Marcela Maksymowicz, et al.
Published: (2021-09-01)

Insight into the Potential Mechanisms of Endocrine Disruption by Dietary Phytoestrogens in the Context of the Etiopathogenesis of Endometriosis
by: Dariusz Szukiewicz
Published: (2023-07-01)

Endocrine Disrupting Chemicals: A Challenge to Child Health
by: Geetha Mani, et al.
Published: (2017-03-01)