The characteristics of hemophilic patients with decreased bone density in Cipto Mangunkusumo Hospital Jakarta
Background: Hemophilia can cause musculoskeletal complications and decreased bone density is one of those complications. The profile of hemophilic patients with decreased bone density in Indonesia is still unknown. Objective: To estimate the proportion of decreased bone density hemophilia and to l...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Indonesia Rheumatology Association
2018-02-01
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| Series: | Indonesian Journal of Rheumatology |
| Online Access: | https://journalrheumatology.or.id/index.php/ijr/article/view/88 |
| _version_ | 1818417410930114560 |
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| author | S Anggoro B Setyohadi L Sukrisman S Setiati |
| author_facet | S Anggoro B Setyohadi L Sukrisman S Setiati |
| author_sort | S Anggoro |
| collection | DOAJ |
| description | Background: Hemophilia can cause musculoskeletal complications and decreased bone density is one of those complications. The profile of hemophilic patients with decreased bone density in Indonesia is still unknown.
Objective: To estimate the proportion of decreased bone density hemophilia and to learn the characteristics of hemophilic patients with decreased bone density.
Methods: This is a cross-sectional study done in June - November 2012. Subjects were adult hemophilic patients from 19-50 years old in Hematology- Oncology outpatient clinic Cipto Mangunkusumo Hospital. Estimated variables were bone density mass, age, body
mass index, physical activity, arthropathy, substitution therapy, HIV, and HCV infection.
Result: 63 subjects were included in the study with median age of 26 years old. The proportion of decreased bone density in hemophilia was 6.3%. Subjects with decreased bone density were younger (19 years old vs 26 years old), have lower BMI (18,6 + 2,8 kg/m2 vs 21,5 + 3,8 kg/m2), used more substitution therapy (4047 IU/month vs 2000 IU/month), and have better clinical arthropathy score. HCV infection happened on 25% subjects with decreased bone density while HIV was on 1.6% of subjects.
Conclusion: Decreased bone density was found in 6.3% of subjects with hemophilia. They were younger, have lower BMI, better joint score, lower infection caused by transfusion, and more bleeding compared with subjects with normal bone density. |
| first_indexed | 2024-12-14T12:06:21Z |
| format | Article |
| id | doaj.art-ff8478de7ab44094945d6ee554e6bec5 |
| institution | Directory Open Access Journal |
| issn | 2086-1435 2581-1142 |
| language | English |
| last_indexed | 2024-12-14T12:06:21Z |
| publishDate | 2018-02-01 |
| publisher | Indonesia Rheumatology Association |
| record_format | Article |
| series | Indonesian Journal of Rheumatology |
| spelling | doaj.art-ff8478de7ab44094945d6ee554e6bec52022-12-21T23:01:52ZengIndonesia Rheumatology AssociationIndonesian Journal of Rheumatology2086-14352581-11422018-02-014110.37275/ijr.v4i1.8888The characteristics of hemophilic patients with decreased bone density in Cipto Mangunkusumo Hospital JakartaS Anggoro0B Setyohadi1L Sukrisman2S Setiati3Department of Internal Medicine, University of Indonesia School of Medicine/ Cipto Mangunkusumo HospitalDepartment of Internal Medicine, University of Indonesia School of Medicine/ Cipto Mangunkusumo HospitalDepartment of Internal Medicine, University of Indonesia School of Medicine/ Cipto Mangunkusumo HospitalDepartment of Internal Medicine, University of Indonesia School of Medicine/ Cipto Mangunkusumo HospitalBackground: Hemophilia can cause musculoskeletal complications and decreased bone density is one of those complications. The profile of hemophilic patients with decreased bone density in Indonesia is still unknown. Objective: To estimate the proportion of decreased bone density hemophilia and to learn the characteristics of hemophilic patients with decreased bone density. Methods: This is a cross-sectional study done in June - November 2012. Subjects were adult hemophilic patients from 19-50 years old in Hematology- Oncology outpatient clinic Cipto Mangunkusumo Hospital. Estimated variables were bone density mass, age, body mass index, physical activity, arthropathy, substitution therapy, HIV, and HCV infection. Result: 63 subjects were included in the study with median age of 26 years old. The proportion of decreased bone density in hemophilia was 6.3%. Subjects with decreased bone density were younger (19 years old vs 26 years old), have lower BMI (18,6 + 2,8 kg/m2 vs 21,5 + 3,8 kg/m2), used more substitution therapy (4047 IU/month vs 2000 IU/month), and have better clinical arthropathy score. HCV infection happened on 25% subjects with decreased bone density while HIV was on 1.6% of subjects. Conclusion: Decreased bone density was found in 6.3% of subjects with hemophilia. They were younger, have lower BMI, better joint score, lower infection caused by transfusion, and more bleeding compared with subjects with normal bone density.https://journalrheumatology.or.id/index.php/ijr/article/view/88 |
| spellingShingle | S Anggoro B Setyohadi L Sukrisman S Setiati The characteristics of hemophilic patients with decreased bone density in Cipto Mangunkusumo Hospital Jakarta Indonesian Journal of Rheumatology |
| title | The characteristics of hemophilic patients with decreased bone density in Cipto Mangunkusumo Hospital Jakarta |
| title_full | The characteristics of hemophilic patients with decreased bone density in Cipto Mangunkusumo Hospital Jakarta |
| title_fullStr | The characteristics of hemophilic patients with decreased bone density in Cipto Mangunkusumo Hospital Jakarta |
| title_full_unstemmed | The characteristics of hemophilic patients with decreased bone density in Cipto Mangunkusumo Hospital Jakarta |
| title_short | The characteristics of hemophilic patients with decreased bone density in Cipto Mangunkusumo Hospital Jakarta |
| title_sort | characteristics of hemophilic patients with decreased bone density in cipto mangunkusumo hospital jakarta |
| url | https://journalrheumatology.or.id/index.php/ijr/article/view/88 |
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