A retrospective analysis of early experience with modified complete primary repair of exstrophy bladder (CPRE) in neonates and children

Objective: To study the problems faced during the surgery and follow-up of modified complete primary repair of exstrophy (CPRE) technique. Initial experience with CPRE and its short- and long-term outcomes with respect to continence status and psychosocial impact are reported. Materials and Methods:...

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Main Authors: Santosh B. Kurbet, Gowda P. Prashanth, Mahantesh V. Patil, Shivaji Mane
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2013-09-01
Series:Indian Journal of Plastic Surgery
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/0970-0358.122015
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author Santosh B. Kurbet
Gowda P. Prashanth
Mahantesh V. Patil
Shivaji Mane
author_facet Santosh B. Kurbet
Gowda P. Prashanth
Mahantesh V. Patil
Shivaji Mane
author_sort Santosh B. Kurbet
collection DOAJ
description Objective: To study the problems faced during the surgery and follow-up of modified complete primary repair of exstrophy (CPRE) technique. Initial experience with CPRE and its short- and long-term outcomes with respect to continence status and psychosocial impact are reported. Materials and Methods: A retrospective review of the hospital case records from March 2008 to September 2012 was performed. Data of patients with bladder exstrophy managed by a single paediatric surgeon using modified CPRE technique were analysed. Quality of life and psychosocial impact of the surgery were assessed using Pediatric Quality of Life Inventory (PedsQL 4.0) and compared with those of typical peers. Results: Eight children (age 4 days-12 years) underwent CPRE using modified Mitchell′s technique. Two patients (25%) experienced early postoperative complications, with infection and fistula developing in one each. All the patients were doing well on follow-up, with variable continence rates and good cosmesis. Mean duration of follow-up was 18.5 months (range 6 months-4 years). Five out of seven (71%) children were continent or partially continent. One case was lost to follow-up. PedsQL scores were comparable with those of age-matched peers in all domains except the social functioning domain in 8-12 years age group (83.53 ± 9.70 vs. 77.86 ± 10.22, P < 0.05). Conclusion: Our preliminary results with modified CPRE in neonates and children have been encouraging. No major complications were observed. Continence rate was satisfactory and cosmetic results were good. Though the technique is being practiced at several Indian centres, there is a paucity of comprehensive Indian data on CPRE.
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spelling doaj.art-ff84c124a65e45f2b2ae8d42506e5f342022-12-21T18:21:39ZengThieme Medical Publishers, Inc.Indian Journal of Plastic Surgery0970-03581998-376X2013-09-01460354955410.4103/0970-0358.122015A retrospective analysis of early experience with modified complete primary repair of exstrophy bladder (CPRE) in neonates and childrenSantosh B. Kurbet0Gowda P. Prashanth1Mahantesh V. Patil2Shivaji Mane3Department of Pediatric Surgery, Dr. Prabhakar Kore Hospital and Medical Research Centre and KLE University′s Jawaharlal Nehru Medical College, Belgaum, KarnatakaDepartment of Pediatrics, Dr. Prabhakar Kore Hospital and Medical Research Centre and KLE University′s Jawaharlal Nehru Medical College, Belgaum, KarnatakaDepartment of Pediatrics, Dr. Prabhakar Kore Hospital and Medical Research Centre and KLE University′s Jawaharlal Nehru Medical College, Belgaum, KarnatakaDepartment of Pediatric Surgery, Grant Medical College and Sir JJ Group of Hospitals, Byculla, Mumbai, Maharashtra, IndiaObjective: To study the problems faced during the surgery and follow-up of modified complete primary repair of exstrophy (CPRE) technique. Initial experience with CPRE and its short- and long-term outcomes with respect to continence status and psychosocial impact are reported. Materials and Methods: A retrospective review of the hospital case records from March 2008 to September 2012 was performed. Data of patients with bladder exstrophy managed by a single paediatric surgeon using modified CPRE technique were analysed. Quality of life and psychosocial impact of the surgery were assessed using Pediatric Quality of Life Inventory (PedsQL 4.0) and compared with those of typical peers. Results: Eight children (age 4 days-12 years) underwent CPRE using modified Mitchell′s technique. Two patients (25%) experienced early postoperative complications, with infection and fistula developing in one each. All the patients were doing well on follow-up, with variable continence rates and good cosmesis. Mean duration of follow-up was 18.5 months (range 6 months-4 years). Five out of seven (71%) children were continent or partially continent. One case was lost to follow-up. PedsQL scores were comparable with those of age-matched peers in all domains except the social functioning domain in 8-12 years age group (83.53 ± 9.70 vs. 77.86 ± 10.22, P < 0.05). Conclusion: Our preliminary results with modified CPRE in neonates and children have been encouraging. No major complications were observed. Continence rate was satisfactory and cosmetic results were good. Though the technique is being practiced at several Indian centres, there is a paucity of comprehensive Indian data on CPRE.http://www.thieme-connect.de/DOI/DOI?10.4103/0970-0358.122015bladder exstrophycomplete primary repairurinary continence
spellingShingle Santosh B. Kurbet
Gowda P. Prashanth
Mahantesh V. Patil
Shivaji Mane
A retrospective analysis of early experience with modified complete primary repair of exstrophy bladder (CPRE) in neonates and children
Indian Journal of Plastic Surgery
bladder exstrophy
complete primary repair
urinary continence
title A retrospective analysis of early experience with modified complete primary repair of exstrophy bladder (CPRE) in neonates and children
title_full A retrospective analysis of early experience with modified complete primary repair of exstrophy bladder (CPRE) in neonates and children
title_fullStr A retrospective analysis of early experience with modified complete primary repair of exstrophy bladder (CPRE) in neonates and children
title_full_unstemmed A retrospective analysis of early experience with modified complete primary repair of exstrophy bladder (CPRE) in neonates and children
title_short A retrospective analysis of early experience with modified complete primary repair of exstrophy bladder (CPRE) in neonates and children
title_sort retrospective analysis of early experience with modified complete primary repair of exstrophy bladder cpre in neonates and children
topic bladder exstrophy
complete primary repair
urinary continence
url http://www.thieme-connect.de/DOI/DOI?10.4103/0970-0358.122015
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