MiR-144-3p Enhances Cardiac Fibrosis After Myocardial Infarction by Targeting PTEN

MiR-144-3p Enhances Cardiac Fibrosis After Myocardial Infarction by Targeting PTEN

Myocardial infarction (MI) may cause heart failure and seriously harm human health. During the genesis of cardiac fibrosis after MI, the proliferation and migration of cardiac fibroblasts contribute to secretion and maintenance of extracellular matrix (ECM) components. Many miRNAs have been highly i...

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Bibliographic Details
Main Authors: Xiaolong Yuan, Jinchun Pan, Lijuan Wen, Baoyong Gong, Jiaqi Li, Hongbin Gao, Weijiang Tan, Shi Liang, Hao Zhang, Xilong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
miR-144-3p
PTEN
cardiac fibrosis
myocardial infarction
extracellular matrix
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00249/full

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