CT-Guided Percutaneous Cryoablation for Lung Metastasis of Colorectal Cancer: A Case Series
Purpose This study aimed to evaluate the efficacy of computed tomography (CT) guided percutaneous cryoablation (CA) for the management of lung metastases in patients with metastatic colorectal cancer (mCRC). Methods Retrospective analysis was performed on 38 mCRC patients with lung metastases, who u...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-09-01
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| Series: | Technology in Cancer Research & Treatment |
| Online Access: | https://doi.org/10.1177/15330338231201508 |
| _version_ | 1797677055230345216 |
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| author | Fu-ming Wang MD Rong Luo MD Jin-ming Tian MD Hang Liu MD Ji-jin Yang MD, PhD |
| author_facet | Fu-ming Wang MD Rong Luo MD Jin-ming Tian MD Hang Liu MD Ji-jin Yang MD, PhD |
| author_sort | Fu-ming Wang MD |
| collection | DOAJ |
| description | Purpose This study aimed to evaluate the efficacy of computed tomography (CT) guided percutaneous cryoablation (CA) for the management of lung metastases in patients with metastatic colorectal cancer (mCRC). Methods Retrospective analysis was performed on 38 mCRC patients with lung metastases, who underwent CT-guided percutaneous CA at our center from May 1, 2020 to November 1, 2021. The technical success rate, 1-year local control (LC) rate, recurrence-free survival (RFS) and treatment-related complications were analyzed. Results The CA procedure was successfully performed in all patients, with a technical success rate of 100%. The 1-year LC rate was 94.7% (36/38), while 16 patients experienced new distant lung metastases during the follow-up period. The median RFS was 20 months (95% CI: 13.0-27.0). The median RFS of patients with and without extrapulmonary metastasis was 15 and 23 months, respectively. Complications were reported in 18 (47.4%) patients following the CA procedure. Pneumothorax was discovered in 15 (39.5%) patients, and five of these patients (13.2%) required chest tube intubation. Two patients (5.3%) presented with hemoptysis during the CA procedure. One patient developed subcutaneous emphysema as detected in the post-procedure follow-up imaging. All patients tolerated the peri-procedural pain well under local anesthesia, and the mean visual analog scale (VAS) score was 2.8. Conclusion Lung CA is a safe and well-tolerated treatment with a satisfactory local control rate for patients with lung metastases derived from mCRC. |
| first_indexed | 2024-03-11T22:39:25Z |
| format | Article |
| id | doaj.art-ff886809bb5f44edab410d5b5e563ce3 |
| institution | Directory Open Access Journal |
| issn | 1533-0338 |
| language | English |
| last_indexed | 2024-03-11T22:39:25Z |
| publishDate | 2023-09-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Technology in Cancer Research & Treatment |
| spelling | doaj.art-ff886809bb5f44edab410d5b5e563ce32023-09-22T09:33:22ZengSAGE PublishingTechnology in Cancer Research & Treatment1533-03382023-09-012210.1177/15330338231201508CT-Guided Percutaneous Cryoablation for Lung Metastasis of Colorectal Cancer: A Case SeriesFu-ming Wang MDRong Luo MDJin-ming Tian MDHang Liu MDJi-jin Yang MD, PhDPurpose This study aimed to evaluate the efficacy of computed tomography (CT) guided percutaneous cryoablation (CA) for the management of lung metastases in patients with metastatic colorectal cancer (mCRC). Methods Retrospective analysis was performed on 38 mCRC patients with lung metastases, who underwent CT-guided percutaneous CA at our center from May 1, 2020 to November 1, 2021. The technical success rate, 1-year local control (LC) rate, recurrence-free survival (RFS) and treatment-related complications were analyzed. Results The CA procedure was successfully performed in all patients, with a technical success rate of 100%. The 1-year LC rate was 94.7% (36/38), while 16 patients experienced new distant lung metastases during the follow-up period. The median RFS was 20 months (95% CI: 13.0-27.0). The median RFS of patients with and without extrapulmonary metastasis was 15 and 23 months, respectively. Complications were reported in 18 (47.4%) patients following the CA procedure. Pneumothorax was discovered in 15 (39.5%) patients, and five of these patients (13.2%) required chest tube intubation. Two patients (5.3%) presented with hemoptysis during the CA procedure. One patient developed subcutaneous emphysema as detected in the post-procedure follow-up imaging. All patients tolerated the peri-procedural pain well under local anesthesia, and the mean visual analog scale (VAS) score was 2.8. Conclusion Lung CA is a safe and well-tolerated treatment with a satisfactory local control rate for patients with lung metastases derived from mCRC.https://doi.org/10.1177/15330338231201508 |
| spellingShingle | Fu-ming Wang MD Rong Luo MD Jin-ming Tian MD Hang Liu MD Ji-jin Yang MD, PhD CT-Guided Percutaneous Cryoablation for Lung Metastasis of Colorectal Cancer: A Case Series Technology in Cancer Research & Treatment |
| title | CT-Guided Percutaneous Cryoablation
for Lung Metastasis of Colorectal Cancer:
A Case Series |
| title_full | CT-Guided Percutaneous Cryoablation
for Lung Metastasis of Colorectal Cancer:
A Case Series |
| title_fullStr | CT-Guided Percutaneous Cryoablation
for Lung Metastasis of Colorectal Cancer:
A Case Series |
| title_full_unstemmed | CT-Guided Percutaneous Cryoablation
for Lung Metastasis of Colorectal Cancer:
A Case Series |
| title_short | CT-Guided Percutaneous Cryoablation
for Lung Metastasis of Colorectal Cancer:
A Case Series |
| title_sort | ct guided percutaneous cryoablation for lung metastasis of colorectal cancer a case series |
| url | https://doi.org/10.1177/15330338231201508 |
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