Lipid-Based Nanostructures for the Delivery of Natural Antimicrobials

Encapsulation can be a suitable strategy to protect natural antimicrobial substances against some harsh conditions of processing and storage and to provide efficient formulations for antimicrobial delivery. Lipid-based nanostructures, including liposomes, solid lipid nanoparticles (SLNs), and nanost...

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Main Authors: Cristian Mauricio Barreto Pinilla, Nathalie Almeida Lopes, Adriano Brandelli
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/12/3587
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author Cristian Mauricio Barreto Pinilla
Nathalie Almeida Lopes
Adriano Brandelli
author_facet Cristian Mauricio Barreto Pinilla
Nathalie Almeida Lopes
Adriano Brandelli
author_sort Cristian Mauricio Barreto Pinilla
collection DOAJ
description Encapsulation can be a suitable strategy to protect natural antimicrobial substances against some harsh conditions of processing and storage and to provide efficient formulations for antimicrobial delivery. Lipid-based nanostructures, including liposomes, solid lipid nanoparticles (SLNs), and nanostructured lipid nanocarriers (NLCs), are valuable systems for the delivery and controlled release of natural antimicrobial substances. These nanostructures have been used as carriers for bacteriocins and other antimicrobial peptides, antimicrobial enzymes, essential oils, and antimicrobial phytochemicals. Most studies are conducted with liposomes, although the potential of SLNs and NLCs as antimicrobial nanocarriers is not yet fully established. Some studies reveal that lipid-based formulations can be used for co-encapsulation of natural antimicrobials, improving their potential to control microbial pathogens.
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spelling doaj.art-ff8a608ff5884e4db24fd240e2b87c672023-11-21T23:45:57ZengMDPI AGMolecules1420-30492021-06-012612358710.3390/molecules26123587Lipid-Based Nanostructures for the Delivery of Natural AntimicrobialsCristian Mauricio Barreto Pinilla0Nathalie Almeida Lopes1Adriano Brandelli2Laboratory of Applied Microbiology and Biochemistry, Institute of Food Science and Technology (ICTA), Federal University of Rio Grande do Sul, Porto Alegre 91501-970, BrazilLaboratory of Applied Microbiology and Biochemistry, Institute of Food Science and Technology (ICTA), Federal University of Rio Grande do Sul, Porto Alegre 91501-970, BrazilLaboratory of Applied Microbiology and Biochemistry, Institute of Food Science and Technology (ICTA), Federal University of Rio Grande do Sul, Porto Alegre 91501-970, BrazilEncapsulation can be a suitable strategy to protect natural antimicrobial substances against some harsh conditions of processing and storage and to provide efficient formulations for antimicrobial delivery. Lipid-based nanostructures, including liposomes, solid lipid nanoparticles (SLNs), and nanostructured lipid nanocarriers (NLCs), are valuable systems for the delivery and controlled release of natural antimicrobial substances. These nanostructures have been used as carriers for bacteriocins and other antimicrobial peptides, antimicrobial enzymes, essential oils, and antimicrobial phytochemicals. Most studies are conducted with liposomes, although the potential of SLNs and NLCs as antimicrobial nanocarriers is not yet fully established. Some studies reveal that lipid-based formulations can be used for co-encapsulation of natural antimicrobials, improving their potential to control microbial pathogens.https://www.mdpi.com/1420-3049/26/12/3587natural antimicrobialsmicrobial safetynanostructuresphospholipidsliposomes
spellingShingle Cristian Mauricio Barreto Pinilla
Nathalie Almeida Lopes
Adriano Brandelli
Lipid-Based Nanostructures for the Delivery of Natural Antimicrobials
Molecules
natural antimicrobials
microbial safety
nanostructures
phospholipids
liposomes
title Lipid-Based Nanostructures for the Delivery of Natural Antimicrobials
title_full Lipid-Based Nanostructures for the Delivery of Natural Antimicrobials
title_fullStr Lipid-Based Nanostructures for the Delivery of Natural Antimicrobials
title_full_unstemmed Lipid-Based Nanostructures for the Delivery of Natural Antimicrobials
title_short Lipid-Based Nanostructures for the Delivery of Natural Antimicrobials
title_sort lipid based nanostructures for the delivery of natural antimicrobials
topic natural antimicrobials
microbial safety
nanostructures
phospholipids
liposomes
url https://www.mdpi.com/1420-3049/26/12/3587
work_keys_str_mv AT cristianmauriciobarretopinilla lipidbasednanostructuresforthedeliveryofnaturalantimicrobials
AT nathaliealmeidalopes lipidbasednanostructuresforthedeliveryofnaturalantimicrobials
AT adrianobrandelli lipidbasednanostructuresforthedeliveryofnaturalantimicrobials