“Black Ovaries”: An Uncommon Case of First Systemic Recurrence of Melanoma
Here we describe a rare case of a 48-year-old woman with a previous history of malignant melanoma (pT2a pathological stage, IB clinical stage) occurring about five years previously. She complained of abdominal pain and pelvic discomfort, diagnosed as a consequence of a bilateral ovarian solid masses...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-05-01
|
| Series: | Reports |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2571-841X/4/2/13 |
| _version_ | 1827692819666436096 |
|---|---|
| author | Gerardo Cazzato Anna Colagrande Francesca Arezzo Leonardo Resta Giuseppe Ingravallo |
| author_facet | Gerardo Cazzato Anna Colagrande Francesca Arezzo Leonardo Resta Giuseppe Ingravallo |
| author_sort | Gerardo Cazzato |
| collection | DOAJ |
| description | Here we describe a rare case of a 48-year-old woman with a previous history of malignant melanoma (pT2a pathological stage, IB clinical stage) occurring about five years previously. She complained of abdominal pain and pelvic discomfort, diagnosed as a consequence of a bilateral ovarian solid masses completely occupying the recto-uterine space. She underwent laparotomy surgery with total hysterectomy and bilateral salpingo-oophorectomy. Gross examination of the excised material revealed an unusual grey-black bilateral ovarian tumor; a histopathological diagnosis of ovarian bilateral metastatic melanoma was made. Imaging study (CT/MRI) did not reveal metastasis in other zones of the body. Melanoma metastasis usually affects the skin, liver, brain and lungs, and rarely gynecological localizations. On the other hand, most bilateral ovarian tumors are comprised of serous carcinoma, mature teratoma and gastrointestinal carcinoma metastasis. Exceptionally, primary ovarian melanoma may arise in mature ovarian cystic teratomas. |
| first_indexed | 2024-03-10T11:31:16Z |
| format | Article |
| id | doaj.art-ff8be93bb83847a09e1752e12a689a63 |
| institution | Directory Open Access Journal |
| issn | 2571-841X |
| language | English |
| last_indexed | 2024-03-10T11:31:16Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Reports |
| spelling | doaj.art-ff8be93bb83847a09e1752e12a689a632023-11-21T19:16:15ZengMDPI AGReports2571-841X2021-05-01421310.3390/reports4020013“Black Ovaries”: An Uncommon Case of First Systemic Recurrence of MelanomaGerardo Cazzato0Anna Colagrande1Francesca Arezzo2Leonardo Resta3Giuseppe Ingravallo4Section of Pathology, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, ItalySection of Pathology, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, ItalyObstetrics and Gynecology Unit, Department of Biomedical Sciences and Human Oncology, University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, ItalySection of Pathology, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, ItalyHere we describe a rare case of a 48-year-old woman with a previous history of malignant melanoma (pT2a pathological stage, IB clinical stage) occurring about five years previously. She complained of abdominal pain and pelvic discomfort, diagnosed as a consequence of a bilateral ovarian solid masses completely occupying the recto-uterine space. She underwent laparotomy surgery with total hysterectomy and bilateral salpingo-oophorectomy. Gross examination of the excised material revealed an unusual grey-black bilateral ovarian tumor; a histopathological diagnosis of ovarian bilateral metastatic melanoma was made. Imaging study (CT/MRI) did not reveal metastasis in other zones of the body. Melanoma metastasis usually affects the skin, liver, brain and lungs, and rarely gynecological localizations. On the other hand, most bilateral ovarian tumors are comprised of serous carcinoma, mature teratoma and gastrointestinal carcinoma metastasis. Exceptionally, primary ovarian melanoma may arise in mature ovarian cystic teratomas.https://www.mdpi.com/2571-841X/4/2/13melanomaovarymetastasis |
| spellingShingle | Gerardo Cazzato Anna Colagrande Francesca Arezzo Leonardo Resta Giuseppe Ingravallo “Black Ovaries”: An Uncommon Case of First Systemic Recurrence of Melanoma Reports melanoma ovary metastasis |
| title | “Black Ovaries”: An Uncommon Case of First Systemic Recurrence of Melanoma |
| title_full | “Black Ovaries”: An Uncommon Case of First Systemic Recurrence of Melanoma |
| title_fullStr | “Black Ovaries”: An Uncommon Case of First Systemic Recurrence of Melanoma |
| title_full_unstemmed | “Black Ovaries”: An Uncommon Case of First Systemic Recurrence of Melanoma |
| title_short | “Black Ovaries”: An Uncommon Case of First Systemic Recurrence of Melanoma |
| title_sort | black ovaries an uncommon case of first systemic recurrence of melanoma |
| topic | melanoma ovary metastasis |
| url | https://www.mdpi.com/2571-841X/4/2/13 |
| work_keys_str_mv | AT gerardocazzato blackovariesanuncommoncaseoffirstsystemicrecurrenceofmelanoma AT annacolagrande blackovariesanuncommoncaseoffirstsystemicrecurrenceofmelanoma AT francescaarezzo blackovariesanuncommoncaseoffirstsystemicrecurrenceofmelanoma AT leonardoresta blackovariesanuncommoncaseoffirstsystemicrecurrenceofmelanoma AT giuseppeingravallo blackovariesanuncommoncaseoffirstsystemicrecurrenceofmelanoma |