Big data evidence of the impact of COVID-19 hospitalizations on mortality rates of non-COVID-19 critically ill patients

Abstract The COVID-19 virus caused a global pandemic leading to a swift policy response. While this response was designed to prevent the spread of the virus and support those with COVID-19, there is growing evidence regarding measurable impacts on non-COVID-19 patients. The paper uses a large datase...

Full description

Bibliographic Details
Main Authors: Bruno Wichmann, Roberta Moreira Wichmann
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40727-z
_version_ 1797453035807440896
author Bruno Wichmann
Roberta Moreira Wichmann
author_facet Bruno Wichmann
Roberta Moreira Wichmann
author_sort Bruno Wichmann
collection DOAJ
description Abstract The COVID-19 virus caused a global pandemic leading to a swift policy response. While this response was designed to prevent the spread of the virus and support those with COVID-19, there is growing evidence regarding measurable impacts on non-COVID-19 patients. The paper uses a large dataset from administrative records of the Brazilian public health system (SUS) to estimate pandemic spillover effects in critically ill health care delivery, i.e. the additional mortality risk that COVID-19 ICU hospitalizations generate on non-COVID-19 patients receiving intensive care. The data contain the universe of ICU hospitalizations in SUS from February 26, 2020 to December 31, 2021. Spillover estimates are obtained from high-dimensional fixed effects regression models that control for a number of unobservable confounders. Our findings indicate that, on average, the pandemic increased the mortality risk of non-COVID-19 ICU patients by 1.296 percentage points, 95% CI 1.145–1.448. The spillover mortality risk is larger for non-COVID patients receiving intensive care due to diseases of the respiratory system, diseases of the skin and subcutaneous tissue, and infectious and parasitic diseases. As of July 2023, the WHO reports more than 6.9 million global deaths due to COVID-19 infection. However, our estimates of spillover effects suggest that the pandemic’s total death toll is much higher.
first_indexed 2024-03-09T15:17:10Z
format Article
id doaj.art-ff90169b0f7e4bac9673f711eece405a
institution Directory Open Access Journal
issn 2045-2322
language English
last_indexed 2024-03-09T15:17:10Z
publishDate 2023-08-01
publisher Nature Portfolio
record_format Article
series Scientific Reports
spelling doaj.art-ff90169b0f7e4bac9673f711eece405a2023-11-26T13:02:15ZengNature PortfolioScientific Reports2045-23222023-08-011311910.1038/s41598-023-40727-zBig data evidence of the impact of COVID-19 hospitalizations on mortality rates of non-COVID-19 critically ill patientsBruno Wichmann0Roberta Moreira Wichmann1Department of Resource Economics & Environmental Sociology, College of Natural and Applied Sciences, University of AlbertaWorld BankAbstract The COVID-19 virus caused a global pandemic leading to a swift policy response. While this response was designed to prevent the spread of the virus and support those with COVID-19, there is growing evidence regarding measurable impacts on non-COVID-19 patients. The paper uses a large dataset from administrative records of the Brazilian public health system (SUS) to estimate pandemic spillover effects in critically ill health care delivery, i.e. the additional mortality risk that COVID-19 ICU hospitalizations generate on non-COVID-19 patients receiving intensive care. The data contain the universe of ICU hospitalizations in SUS from February 26, 2020 to December 31, 2021. Spillover estimates are obtained from high-dimensional fixed effects regression models that control for a number of unobservable confounders. Our findings indicate that, on average, the pandemic increased the mortality risk of non-COVID-19 ICU patients by 1.296 percentage points, 95% CI 1.145–1.448. The spillover mortality risk is larger for non-COVID patients receiving intensive care due to diseases of the respiratory system, diseases of the skin and subcutaneous tissue, and infectious and parasitic diseases. As of July 2023, the WHO reports more than 6.9 million global deaths due to COVID-19 infection. However, our estimates of spillover effects suggest that the pandemic’s total death toll is much higher.https://doi.org/10.1038/s41598-023-40727-z
spellingShingle Bruno Wichmann
Roberta Moreira Wichmann
Big data evidence of the impact of COVID-19 hospitalizations on mortality rates of non-COVID-19 critically ill patients
Scientific Reports
title Big data evidence of the impact of COVID-19 hospitalizations on mortality rates of non-COVID-19 critically ill patients
title_full Big data evidence of the impact of COVID-19 hospitalizations on mortality rates of non-COVID-19 critically ill patients
title_fullStr Big data evidence of the impact of COVID-19 hospitalizations on mortality rates of non-COVID-19 critically ill patients
title_full_unstemmed Big data evidence of the impact of COVID-19 hospitalizations on mortality rates of non-COVID-19 critically ill patients
title_short Big data evidence of the impact of COVID-19 hospitalizations on mortality rates of non-COVID-19 critically ill patients
title_sort big data evidence of the impact of covid 19 hospitalizations on mortality rates of non covid 19 critically ill patients
url https://doi.org/10.1038/s41598-023-40727-z
work_keys_str_mv AT brunowichmann bigdataevidenceoftheimpactofcovid19hospitalizationsonmortalityratesofnoncovid19criticallyillpatients
AT robertamoreirawichmann bigdataevidenceoftheimpactofcovid19hospitalizationsonmortalityratesofnoncovid19criticallyillpatients