The association between ECG criteria and Echo criteria for left ventricular hypertrophy in a general Chinese population
Abstract Background Several ECG criteria have been widely used for diagnosis of left ventricular hypertrophy (LVH) in clinical practice. However, their performance in a general Chinese population is limited. Methods and results A multi‐stage, stratified cluster sampling across China was performed an...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-09-01
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| Series: | Annals of Noninvasive Electrocardiology |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/anec.12880 |
| _version_ | 1818718346262085632 |
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| author | Tingting Lv Yifang Yuan Jing Yang Guijin Wang Lingyun Kong Huijuan Li Xingjie Li Yingxian Sun Xuewen Li Zheng Zhang Xiaoshu Cheng Lirong Wu Xuerui Tan Bing Han Hua Li Zhaoguo Zhang Jiayu Wang Yangfeng Wu Yanfang Wang Jihong Guo Ping Zhang |
| author_facet | Tingting Lv Yifang Yuan Jing Yang Guijin Wang Lingyun Kong Huijuan Li Xingjie Li Yingxian Sun Xuewen Li Zheng Zhang Xiaoshu Cheng Lirong Wu Xuerui Tan Bing Han Hua Li Zhaoguo Zhang Jiayu Wang Yangfeng Wu Yanfang Wang Jihong Guo Ping Zhang |
| author_sort | Tingting Lv |
| collection | DOAJ |
| description | Abstract Background Several ECG criteria have been widely used for diagnosis of left ventricular hypertrophy (LVH) in clinical practice. However, their performance in a general Chinese population is limited. Methods and results A multi‐stage, stratified cluster sampling across China was performed and 7415 representative Chinese adults aged 18–85 years were analyzed. ECG was collected by using GE MAC 5500 machine. The association between five ECG‐LVH criteria (i.e., Peguero–Lo Presti, Cornell, Cornell product, Sokolow–Lyon and Sokolow–Lyon product) and echocardiographic LVH (Echo‐LVH) was assessed by Pearson's correlation, diagnostic statistics like predictive values, and receiver operating characteristics (ROC) curve. We found that the prevalence of the Echo‐LVH was 11% while ECG‐LVH ranged from 3% to 27%. All ECG‐LVH criteria had high negative predictive value (NPV) (89%) and specificity (73–96%) but low positive predictive value (PPV) (12–24%) and sensitivity (4–29%). The newly Peguero–Lo Presti criteria had higher sensitivity (29%) but lower specificity (73%) and accuracy (68%) compared with other criteria. Cornell product had the best diagnostic performance (AUC: 0.59), as well as the highest specificity (96%) and accuracy (86%) but lowest sensitivity (4%). Among single‐lead components of ECG criteria, RaVL voltage and QRS duration performed relatively better than others. Hypertensive and older individuals had higher sensitivity but lower specificity and accuracy than their counterparts. Conclusion ECG‐LVH criteria had high NPV to detect Echo‐LVH. Though with higher sensitivity, Peguero–Lo Presti criteria did not have better diagnostic performance to detect Echo‐LVH. RaVL and QRS duration had stronger association with Echo‐LVH among all single‐lead components. |
| first_indexed | 2024-12-17T19:49:35Z |
| format | Article |
| id | doaj.art-ff9439b25eb64f3fb93e192ff6a5b82b |
| institution | Directory Open Access Journal |
| issn | 1082-720X 1542-474X |
| language | English |
| last_indexed | 2024-12-17T19:49:35Z |
| publishDate | 2021-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Annals of Noninvasive Electrocardiology |
| spelling | doaj.art-ff9439b25eb64f3fb93e192ff6a5b82b2022-12-21T21:34:47ZengWileyAnnals of Noninvasive Electrocardiology1082-720X1542-474X2021-09-01265n/an/a10.1111/anec.12880The association between ECG criteria and Echo criteria for left ventricular hypertrophy in a general Chinese populationTingting Lv0Yifang Yuan1Jing Yang2Guijin Wang3Lingyun Kong4Huijuan Li5Xingjie Li6Yingxian Sun7Xuewen Li8Zheng Zhang9Xiaoshu Cheng10Lirong Wu11Xuerui Tan12Bing Han13Hua Li14Zhaoguo Zhang15Jiayu Wang16Yangfeng Wu17Yanfang Wang18Jihong Guo19Ping Zhang20Department of Cardiology Tsinghua University, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine Beijing ChinaPeking University Clinical Research Institute Beijing ChinaDepartment of Cardiology Tsinghua University, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine Beijing ChinaDepartment of electronic engineering Tsinghua University Beijing ChinaDepartment of Cardiology Tsinghua University, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine Beijing ChinaPeking University Clinical Research Institute Beijing ChinaDepartment of Cardiology Jining NO. 1 People’s Hospital Jining ChinaDepartment of cardiology First Affiliated Hospital of China Medical University Shenyang ChinaDepartment of cardiology Shanxi Academy of medical sciences, Shanxi Dayi Hospital Taiyuan ChinaDepartment of Cardiology The First Hospital of Lanzhou University Lanzhou Gansu ChinaDepartment of Cardiology The Second Affiliated Hospital of Nanchang University Nanchang Jiangxi ChinaDepartment of cardiology The Affiliated Hospital of Guiyang Medical College Guiyang ChinaDepartment of Cardiology The First Affiliated Hospital of Shantou University Medical College Shantou ChinaDepartment of cardiology Xuzhou Central Hospital Xuzhou ChinaDepartment of Cardiology Tsinghua University, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine Beijing ChinaDepartment of cardiology First Hospital of Integrated Chinese and Western Medicine Beijing ChinaDepartment of cardiology People’s Hospital of peking University Beijing ChinaPeking University Clinical Research Institute Beijing ChinaPeking University Clinical Research Institute Beijing ChinaDepartment of cardiology People’s Hospital of peking University Beijing ChinaDepartment of Cardiology Tsinghua University, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine Beijing ChinaAbstract Background Several ECG criteria have been widely used for diagnosis of left ventricular hypertrophy (LVH) in clinical practice. However, their performance in a general Chinese population is limited. Methods and results A multi‐stage, stratified cluster sampling across China was performed and 7415 representative Chinese adults aged 18–85 years were analyzed. ECG was collected by using GE MAC 5500 machine. The association between five ECG‐LVH criteria (i.e., Peguero–Lo Presti, Cornell, Cornell product, Sokolow–Lyon and Sokolow–Lyon product) and echocardiographic LVH (Echo‐LVH) was assessed by Pearson's correlation, diagnostic statistics like predictive values, and receiver operating characteristics (ROC) curve. We found that the prevalence of the Echo‐LVH was 11% while ECG‐LVH ranged from 3% to 27%. All ECG‐LVH criteria had high negative predictive value (NPV) (89%) and specificity (73–96%) but low positive predictive value (PPV) (12–24%) and sensitivity (4–29%). The newly Peguero–Lo Presti criteria had higher sensitivity (29%) but lower specificity (73%) and accuracy (68%) compared with other criteria. Cornell product had the best diagnostic performance (AUC: 0.59), as well as the highest specificity (96%) and accuracy (86%) but lowest sensitivity (4%). Among single‐lead components of ECG criteria, RaVL voltage and QRS duration performed relatively better than others. Hypertensive and older individuals had higher sensitivity but lower specificity and accuracy than their counterparts. Conclusion ECG‐LVH criteria had high NPV to detect Echo‐LVH. Though with higher sensitivity, Peguero–Lo Presti criteria did not have better diagnostic performance to detect Echo‐LVH. RaVL and QRS duration had stronger association with Echo‐LVH among all single‐lead components.https://doi.org/10.1111/anec.12880ECGechocardiographyhypertensionleft ventricular hypertrophy |
| spellingShingle | Tingting Lv Yifang Yuan Jing Yang Guijin Wang Lingyun Kong Huijuan Li Xingjie Li Yingxian Sun Xuewen Li Zheng Zhang Xiaoshu Cheng Lirong Wu Xuerui Tan Bing Han Hua Li Zhaoguo Zhang Jiayu Wang Yangfeng Wu Yanfang Wang Jihong Guo Ping Zhang The association between ECG criteria and Echo criteria for left ventricular hypertrophy in a general Chinese population Annals of Noninvasive Electrocardiology ECG echocardiography hypertension left ventricular hypertrophy |
| title | The association between ECG criteria and Echo criteria for left ventricular hypertrophy in a general Chinese population |
| title_full | The association between ECG criteria and Echo criteria for left ventricular hypertrophy in a general Chinese population |
| title_fullStr | The association between ECG criteria and Echo criteria for left ventricular hypertrophy in a general Chinese population |
| title_full_unstemmed | The association between ECG criteria and Echo criteria for left ventricular hypertrophy in a general Chinese population |
| title_short | The association between ECG criteria and Echo criteria for left ventricular hypertrophy in a general Chinese population |
| title_sort | association between ecg criteria and echo criteria for left ventricular hypertrophy in a general chinese population |
| topic | ECG echocardiography hypertension left ventricular hypertrophy |
| url | https://doi.org/10.1111/anec.12880 |
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