PECULIARITIES OF RADIATION DIAGNOSTIC OF LUNGS WITH CYSTIC FIBROSIS

Our method was used to clarify the possibilities of diagnostic in case of cystic fibrosis and the installation of a computer tomography place in a diagnostic algorithm. Consequently we have analyzed the results of cases of 5 patients at the age from 19 to 25 years with the diagnosis of cystic fibros...

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Main Authors: Artem Malysh, Fedir Prytkov, Nataliia Morozova, Mykhailo Tkachenko
Format: Article
Language:English
Published: Bogomolets National Medical University 2019-06-01
Series:Ukrainian Scientific Medical Youth Journal
Subjects:
Online Access:https://mmj.nmuofficial.com/index.php/journal/article/view/121
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author Artem Malysh
Fedir Prytkov
Nataliia Morozova
Mykhailo Tkachenko
author_facet Artem Malysh
Fedir Prytkov
Nataliia Morozova
Mykhailo Tkachenko
author_sort Artem Malysh
collection DOAJ
description Our method was used to clarify the possibilities of diagnostic in case of cystic fibrosis and the installation of a computer tomography place in a diagnostic algorithm. Consequently we have analyzed the results of cases of 5 patients at the age from 19 to 25 years with the diagnosis of cystic fibrosis confirmed by sweat samples and genetic investigations. From September 2017 to 2018, the patients were placed in the infection epidemic department No. 2 of Oleksandrivskiy Clinical Hospital die to complications of the main disease. The patients were in the group of middle and high level of severity, respiratory failure II, III stages. These patients were dynamically examined by digital radiography of the chest cavity organs “Radrex” by Toshiba. All of the patients were united by an young age, asthenic and low nutrition body structure, short stature and prolonged anamnesis from early childhood, anamnesis of respiratory diseases, acute respiratory viral infections, bronchitis, sinusitis of the maxillary antrum. It was proved that the results obtained by radiography are typical for CF, but not specific, as well as they could be found in other diffuse lung diseases. After multispiral Computer tomography scan, we have found the main symptoms of cystic fibrosis, such as: total systemic damage of bronchopulmonary structures, two-sides character of pulmonary bronchiectasis . The presence of pronounced dilation of the bronchi of all orders, at least 200% of the original size, with a consolidation and thickening of their walls: a symptom of "ring" and the symptom of "paired strips" and filling of abruptly dilated bronchi of all calibers with a viscous secretion and as a result of this the mucous plugs are formed. Conclusion. The results of the X-ray examination are typical for CF and not specific, as well as for other diffuse pulmonary diseases. Computer tomography can be used for diagnostics of thin structurally functional particles characteristic for cystic fibrosis. It has also been established that the expression of morphological changes of cystic fibrosis are increased with the age of the patients. CT scan is the most useful for the detection morphological and functional changes for cystic fibrosis. Moreover, the CT scan is able to improve the early diagnoses for lungs pathology among the adolescent and the adults, and decrease the period of expectation of the result of the treatment.
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spelling doaj.art-ff961a996e0c4150bb420788b835697e2022-12-22T02:54:36ZengBogomolets National Medical UniversityUkrainian Scientific Medical Youth Journal2786-66612786-667X2019-06-012(110)132010.32345/USMYJ.2(110).2019.13-20121PECULIARITIES OF RADIATION DIAGNOSTIC OF LUNGS WITH CYSTIC FIBROSISArtem Malysh0Fedir Prytkov1Nataliia Morozova2Mykhailo Tkachenko3Student of the 5th year, 8th group of the 2nd medical faculty the National Medical University named after O.O. BohomoletsStudent of the 5th year, 7th group of the 2nd medical faculty the National Medical University named after O.O. BohomoletsMD, Associate Professor, Work in the Department of radiology and radiation medicine of the National Medical University named after O.O. BohomoletsDoctor of Medical Sciences, Professor, Head of the Department of radiology and radiation medicine of the National Medical University named after O.O. BohomoletsOur method was used to clarify the possibilities of diagnostic in case of cystic fibrosis and the installation of a computer tomography place in a diagnostic algorithm. Consequently we have analyzed the results of cases of 5 patients at the age from 19 to 25 years with the diagnosis of cystic fibrosis confirmed by sweat samples and genetic investigations. From September 2017 to 2018, the patients were placed in the infection epidemic department No. 2 of Oleksandrivskiy Clinical Hospital die to complications of the main disease. The patients were in the group of middle and high level of severity, respiratory failure II, III stages. These patients were dynamically examined by digital radiography of the chest cavity organs “Radrex” by Toshiba. All of the patients were united by an young age, asthenic and low nutrition body structure, short stature and prolonged anamnesis from early childhood, anamnesis of respiratory diseases, acute respiratory viral infections, bronchitis, sinusitis of the maxillary antrum. It was proved that the results obtained by radiography are typical for CF, but not specific, as well as they could be found in other diffuse lung diseases. After multispiral Computer tomography scan, we have found the main symptoms of cystic fibrosis, such as: total systemic damage of bronchopulmonary structures, two-sides character of pulmonary bronchiectasis . The presence of pronounced dilation of the bronchi of all orders, at least 200% of the original size, with a consolidation and thickening of their walls: a symptom of "ring" and the symptom of "paired strips" and filling of abruptly dilated bronchi of all calibers with a viscous secretion and as a result of this the mucous plugs are formed. Conclusion. The results of the X-ray examination are typical for CF and not specific, as well as for other diffuse pulmonary diseases. Computer tomography can be used for diagnostics of thin structurally functional particles characteristic for cystic fibrosis. It has also been established that the expression of morphological changes of cystic fibrosis are increased with the age of the patients. CT scan is the most useful for the detection morphological and functional changes for cystic fibrosis. Moreover, the CT scan is able to improve the early diagnoses for lungs pathology among the adolescent and the adults, and decrease the period of expectation of the result of the treatment.https://mmj.nmuofficial.com/index.php/journal/article/view/121computer tomography, cystic fibrosis, diagnostic imaging, differential diagnostic digital radiography, mucoviscidosis, mucous plugs
spellingShingle Artem Malysh
Fedir Prytkov
Nataliia Morozova
Mykhailo Tkachenko
PECULIARITIES OF RADIATION DIAGNOSTIC OF LUNGS WITH CYSTIC FIBROSIS
Ukrainian Scientific Medical Youth Journal
computer tomography, cystic fibrosis, diagnostic imaging, differential diagnostic digital radiography, mucoviscidosis, mucous plugs
title PECULIARITIES OF RADIATION DIAGNOSTIC OF LUNGS WITH CYSTIC FIBROSIS
title_full PECULIARITIES OF RADIATION DIAGNOSTIC OF LUNGS WITH CYSTIC FIBROSIS
title_fullStr PECULIARITIES OF RADIATION DIAGNOSTIC OF LUNGS WITH CYSTIC FIBROSIS
title_full_unstemmed PECULIARITIES OF RADIATION DIAGNOSTIC OF LUNGS WITH CYSTIC FIBROSIS
title_short PECULIARITIES OF RADIATION DIAGNOSTIC OF LUNGS WITH CYSTIC FIBROSIS
title_sort peculiarities of radiation diagnostic of lungs with cystic fibrosis
topic computer tomography, cystic fibrosis, diagnostic imaging, differential diagnostic digital radiography, mucoviscidosis, mucous plugs
url https://mmj.nmuofficial.com/index.php/journal/article/view/121
work_keys_str_mv AT artemmalysh peculiaritiesofradiationdiagnosticoflungswithcysticfibrosis
AT fedirprytkov peculiaritiesofradiationdiagnosticoflungswithcysticfibrosis
AT nataliiamorozova peculiaritiesofradiationdiagnosticoflungswithcysticfibrosis
AT mykhailotkachenko peculiaritiesofradiationdiagnosticoflungswithcysticfibrosis