Salvianolic acid B ameliorates neuroinflammation and neuronal injury via blocking NLRP3 inflammasome and promoting SIRT1 in experimental subarachnoid hemorrhage

Salvianolic acid B ameliorates neuroinflammation and neuronal injury via blocking NLRP3 inflammasome and promoting SIRT1 in experimental subarachnoid hemorrhage

The nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) inflammasome-mediated immuno-inflammatory response plays a critical role in exacerbating early brain injury (EBI) after subarachnoid hemorrhage (SAH). Salvianolic acid B (SalB) has previously b...

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Bibliographic Details
Main Authors: Dayong Xia, Jinlong Yuan, Degang Wu, Haibin Dai, Zong Zhuang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
NLRP3
salvianolic acid B
subarachnoid hemorrhage
sirtuin 1
MCC950
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1159958/full

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