Diffuse terahertz spectroscopy in turbid media using a wavelet-based bimodality spectral analysis

Abstract Current terahertz (THz) spectroscopy techniques only use the coherent light beam for spectral imaging. In the presence of electromagnetic scattering, however, the scattering-mitigated incoherent beams allow for flexible emitter-detector geometries, which enable applications such as seeing t...

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Main Authors: Mahmoud E. Khani, Omar B. Osman, M. Hassan Arbab
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-02068-7
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author Mahmoud E. Khani
Omar B. Osman
M. Hassan Arbab
author_facet Mahmoud E. Khani
Omar B. Osman
M. Hassan Arbab
author_sort Mahmoud E. Khani
collection DOAJ
description Abstract Current terahertz (THz) spectroscopy techniques only use the coherent light beam for spectral imaging. In the presence of electromagnetic scattering, however, the scattering-mitigated incoherent beams allow for flexible emitter-detector geometries, which enable applications such as seeing through turbid media. Despite this potential, THz spectroscopy using diffuse waves has not been demonstrated. The main obstacles are the very poor signal to noise ratios of the diffused fields and the resonance-like spectral artifacts due to multiple Mie scattering events that obscure the material absorption signatures. In this work, we demonstrate diffuse THz spectroscopy of a heterogeneous sample through turbid media using a novel technique based on the wavelet multiresolution analysis and the bimodality coefficient spectrum, which we define here for the first time using the skewness and kurtosis of the spectral images. The proposed method yields broadband and simultaneous material characterization at detection angles as high as 90° with respect to the incident beam. We determined the accuracy of the wavelet-based diffuse spectroscopy at oblique detection angles, by evaluating the area under the receiver operating characteristic curves, to be higher than 95%. This technique is agnostic to any a priori information on the spectral signatures of the sample materials or the characteristics of the scattering medium, and can be expanded for other broadband spectroscopic modalities.
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spelling doaj.art-ff9b439960094070bc7b0b3492c73b7f2022-12-21T21:46:15ZengNature PortfolioScientific Reports2045-23222021-11-0111111310.1038/s41598-021-02068-7Diffuse terahertz spectroscopy in turbid media using a wavelet-based bimodality spectral analysisMahmoud E. Khani0Omar B. Osman1M. Hassan Arbab2Department of Biomedical Engineering, Stony Brook UniversityDepartment of Biomedical Engineering, Stony Brook UniversityDepartment of Biomedical Engineering, Stony Brook UniversityAbstract Current terahertz (THz) spectroscopy techniques only use the coherent light beam for spectral imaging. In the presence of electromagnetic scattering, however, the scattering-mitigated incoherent beams allow for flexible emitter-detector geometries, which enable applications such as seeing through turbid media. Despite this potential, THz spectroscopy using diffuse waves has not been demonstrated. The main obstacles are the very poor signal to noise ratios of the diffused fields and the resonance-like spectral artifacts due to multiple Mie scattering events that obscure the material absorption signatures. In this work, we demonstrate diffuse THz spectroscopy of a heterogeneous sample through turbid media using a novel technique based on the wavelet multiresolution analysis and the bimodality coefficient spectrum, which we define here for the first time using the skewness and kurtosis of the spectral images. The proposed method yields broadband and simultaneous material characterization at detection angles as high as 90° with respect to the incident beam. We determined the accuracy of the wavelet-based diffuse spectroscopy at oblique detection angles, by evaluating the area under the receiver operating characteristic curves, to be higher than 95%. This technique is agnostic to any a priori information on the spectral signatures of the sample materials or the characteristics of the scattering medium, and can be expanded for other broadband spectroscopic modalities.https://doi.org/10.1038/s41598-021-02068-7
spellingShingle Mahmoud E. Khani
Omar B. Osman
M. Hassan Arbab
Diffuse terahertz spectroscopy in turbid media using a wavelet-based bimodality spectral analysis
Scientific Reports
title Diffuse terahertz spectroscopy in turbid media using a wavelet-based bimodality spectral analysis
title_full Diffuse terahertz spectroscopy in turbid media using a wavelet-based bimodality spectral analysis
title_fullStr Diffuse terahertz spectroscopy in turbid media using a wavelet-based bimodality spectral analysis
title_full_unstemmed Diffuse terahertz spectroscopy in turbid media using a wavelet-based bimodality spectral analysis
title_short Diffuse terahertz spectroscopy in turbid media using a wavelet-based bimodality spectral analysis
title_sort diffuse terahertz spectroscopy in turbid media using a wavelet based bimodality spectral analysis
url https://doi.org/10.1038/s41598-021-02068-7
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AT mhassanarbab diffuseterahertzspectroscopyinturbidmediausingawaveletbasedbimodalityspectralanalysis