The Risks of “Getting High” on Over-the-Counter Drugs during Pregnancy

Easy access to over-the-counter (OTC) drugs makes it possible to procure active substances that normally used in therapeutic doses do not raise health problems. The use of high doses of OTC drugs containing codeine, loperamide, pseudoephedrine, diphenhydramine or dimenhydrinate, as well as the use o...

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Main Authors: Bianca-Eugenia Ősz, Ruxandra Ștefănescu, Andreea Sălcudean, George Jîtcă, Camil-Eugen Vari
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Scientia Pharmaceutica
Subjects:
Online Access:https://www.mdpi.com/2218-0532/92/1/7
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author Bianca-Eugenia Ősz
Ruxandra Ștefănescu
Andreea Sălcudean
George Jîtcă
Camil-Eugen Vari
author_facet Bianca-Eugenia Ősz
Ruxandra Ștefănescu
Andreea Sălcudean
George Jîtcă
Camil-Eugen Vari
author_sort Bianca-Eugenia Ősz
collection DOAJ
description Easy access to over-the-counter (OTC) drugs makes it possible to procure active substances that normally used in therapeutic doses do not raise health problems. The use of high doses of OTC drugs containing codeine, loperamide, pseudoephedrine, diphenhydramine or dimenhydrinate, as well as the use of benzidamine systemically raises concerns regarding the increase in units sold. These drugs are used for recreational or euphorizing purposes, including by young women of childbearing age, psychoactive substance users representing a risk group in terms of the possibility of an unplanned pregnancy. Abusive consumption of OTC products during pregnancy is harmful, with consequences for both fetal and late development that can occur in the infant. This literature review presents the risks (teratogenicity, fetal toxicity, neonatal abstinence syndrome, etc.) associated with the use of potentially psychoactive OTC drugs to emphasize the importance of re-evaluating OTC classification and dispensing.
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spelling doaj.art-ff9d2511cd4e452eb2c9f9bba0134eb12024-03-27T14:03:26ZengMDPI AGScientia Pharmaceutica0036-87092218-05322024-01-01921710.3390/scipharm92010007The Risks of “Getting High” on Over-the-Counter Drugs during PregnancyBianca-Eugenia Ősz0Ruxandra Ștefănescu1Andreea Sălcudean2George Jîtcă3Camil-Eugen Vari4Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, RomaniaDepartment of Pharmacognosy and Phytotherapy, Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, RomaniaDepartment of Ethics and Social Sciences, Faculty of Medicine, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, RomaniaDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, RomaniaDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, RomaniaEasy access to over-the-counter (OTC) drugs makes it possible to procure active substances that normally used in therapeutic doses do not raise health problems. The use of high doses of OTC drugs containing codeine, loperamide, pseudoephedrine, diphenhydramine or dimenhydrinate, as well as the use of benzidamine systemically raises concerns regarding the increase in units sold. These drugs are used for recreational or euphorizing purposes, including by young women of childbearing age, psychoactive substance users representing a risk group in terms of the possibility of an unplanned pregnancy. Abusive consumption of OTC products during pregnancy is harmful, with consequences for both fetal and late development that can occur in the infant. This literature review presents the risks (teratogenicity, fetal toxicity, neonatal abstinence syndrome, etc.) associated with the use of potentially psychoactive OTC drugs to emphasize the importance of re-evaluating OTC classification and dispensing.https://www.mdpi.com/2218-0532/92/1/7over-the-counter drugscodeinepseudoephedrineloperamidediphenhydraminedimenhydrinate
spellingShingle Bianca-Eugenia Ősz
Ruxandra Ștefănescu
Andreea Sălcudean
George Jîtcă
Camil-Eugen Vari
The Risks of “Getting High” on Over-the-Counter Drugs during Pregnancy
Scientia Pharmaceutica
over-the-counter drugs
codeine
pseudoephedrine
loperamide
diphenhydramine
dimenhydrinate
title The Risks of “Getting High” on Over-the-Counter Drugs during Pregnancy
title_full The Risks of “Getting High” on Over-the-Counter Drugs during Pregnancy
title_fullStr The Risks of “Getting High” on Over-the-Counter Drugs during Pregnancy
title_full_unstemmed The Risks of “Getting High” on Over-the-Counter Drugs during Pregnancy
title_short The Risks of “Getting High” on Over-the-Counter Drugs during Pregnancy
title_sort risks of getting high on over the counter drugs during pregnancy
topic over-the-counter drugs
codeine
pseudoephedrine
loperamide
diphenhydramine
dimenhydrinate
url https://www.mdpi.com/2218-0532/92/1/7
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