The prognostic value of a combined immune score in tumor and immune cells assessed by immunohistochemistry in triple-negative breast cancer

The prognostic value of a combined immune score in tumor and immune cells assessed by immunohistochemistry in triple-negative breast cancer

Abstract Background This study aimed to develop a novel combined immune score (CIS)-based model assessing prognosis in triple-negative breast cancer (TNBC). Methods The expression of eight immune markers (PD-1, PD-L1, PD-L2, IDO, TIM3, OX40, OX40L, and H7-H2) was assessed with immunohistochemistry o...

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Bibliographic Details
Main Authors: Ji Eun Choi, Jae Seok Lee, Min-Sun Jin, Ilias P. Nikas, Kwangsoo Kim, Sunah Yang, Soo Young Park, Jiwon Koh, Sohyeon Yang, Seock-Ah Im, Han Suk Ryu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Breast Cancer Research
Subjects:
Triple-negative breast cancer (TNBC)
Immune checkpoint proteins
Prognostic model
Combined immune score
Programmed death ligand 1 (PD-L1)
Overall survival (OS)
Online Access:https://doi.org/10.1186/s13058-023-01710-8

Internet

https://doi.org/10.1186/s13058-023-01710-8

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