Initial Events in Bacterial Transcription Initiation

Initial Events in Bacterial Transcription Initiation

Transcription initiation is a highly regulated step of gene expression. Here, we discuss the series of large conformational changes set in motion by initial specific binding of bacterial RNA polymerase (RNAP) to promoter DNA and their relevance for regulation. Bending and wrapping of the upstream du...

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Bibliographic Details
Main Authors: Emily F. Ruff, M. Thomas Record, Irina Artsimovitch
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Biomolecules
Subjects:
RNA polymerase
promoter
kinetics
mechanism
transcription regulation
Online Access:http://www.mdpi.com/2218-273X/5/2/1035

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