Colitis Is Associated with Loss of the Histidine Phosphatase LHPP and Upregulation of Histidine Phosphorylation in Intestinal Epithelial Cells

Colitis Is Associated with Loss of the Histidine Phosphatase LHPP and Upregulation of Histidine Phosphorylation in Intestinal Epithelial Cells

Protein histidine phosphorylation (pHis) is a posttranslational modification involved in cell cycle regulation, ion channel activity and phagocytosis. Using novel monoclonal antibodies to detect pHis, we previously reported that the loss of the histidine phosphatase LHPP (phospholysine phosphohistid...

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Bibliographic Details
Main Authors: Markus Linder, Dritan Liko, Venkatesh Kancherla, Salvatore Piscuoglio, Michael N. Hall
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomedicines
Subjects:
histidine phosphorylation
LHPP
inflammatory bowel disease
colitis
Online Access:https://www.mdpi.com/2227-9059/11/8/2158

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