Factors Affecting Immunosuppressive Medication Adherence in Liver Transplant Recipients with Poor Adherence: A Qualitative Study
Zeliha Ozdemir Koken,1 Rana Elcin Sezer Ceren,1 Sabri Karahan,2 Osman Abbasoglu3 1Surgical Nursing Department, Hacettepe University Faculty of Nursing, Ankara, Turkiye; 2Surgical Nursing Department, Harran University, Faculty of Health Science, Sanliurfa, Turkiye; 3General Surgery Department, Hacett...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-04-01
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| Series: | Patient Preference and Adherence |
| Subjects: | |
| Online Access: | https://www.dovepress.com/factors-affecting-immunosuppressive-medication-adherence-in-liver-tran-peer-reviewed-fulltext-article-PPA |
| _version_ | 1797848482868887552 |
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| author | Ozdemir Koken Z Sezer Ceren RE Karahan S Abbasoglu O |
| author_facet | Ozdemir Koken Z Sezer Ceren RE Karahan S Abbasoglu O |
| author_sort | Ozdemir Koken Z |
| collection | DOAJ |
| description | Zeliha Ozdemir Koken,1 Rana Elcin Sezer Ceren,1 Sabri Karahan,2 Osman Abbasoglu3 1Surgical Nursing Department, Hacettepe University Faculty of Nursing, Ankara, Turkiye; 2Surgical Nursing Department, Harran University, Faculty of Health Science, Sanliurfa, Turkiye; 3General Surgery Department, Hacettepe University Faculty of Medicine, Ankara, TurkiyeCorrespondence: Zeliha Ozdemir Koken, Surgical Nursing Department, Hacettepe University Faculty of Nursing, Ankara, Turkiye, Email zeliha.ozdemir@hacettepe.edu.trPurpose: Preserving graft functions and preventing rejection is closely related to immunosuppressive medication adherence in liver transplant recipients. Therefore, it is essential to determine factors affecting immunosuppressive medication use positively or negatively in liver transplant recipients. This study aimed to explore the use of immunosuppressive medication experience in liver transplant recipients with poor adherence and reveal the factors affecting the medication adherence.Material and Methods: The study was conducted as a qualitative study with phenomenological approach. Seven adult liver transplant recipients were included in this study, who had poor adherence to immunosuppressive medication. Data was collected via in-depth personal interviews. Data analysis was conducted through inductive content analysis with three steps of preparation, organization, and reporting phases.Results: Content analysis revealed four main categories, nine categories and 31 sub-categories. Four main categories emerged from the interview data: medication adherence perception, types of medication non-adherence, factors affecting medication adherence negatively and factors affecting medication adherence positively.Conclusion: This study explored that there are several factors affecting immunosuppressive medication adherence among liver transplant recipients, both positively and negatively. In order to achieve liver transplant recipients’ total adherence to immunosuppressive medication, the factors affecting medication adherence positively and negatively should be understood. The study results are expected to contribute developing strategies to improve immunosuppressive medication adherence in liver transplant recipients.Keywords: immunosuppressive, liver transplant, medication adherence, medication non-adherence |
| first_indexed | 2024-04-09T18:28:15Z |
| format | Article |
| id | doaj.art-ffac8f6b82c143dbac4661adeaea5574 |
| institution | Directory Open Access Journal |
| issn | 1177-889X |
| language | English |
| last_indexed | 2024-04-09T18:28:15Z |
| publishDate | 2023-04-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Patient Preference and Adherence |
| spelling | doaj.art-ffac8f6b82c143dbac4661adeaea55742023-04-11T19:05:00ZengDove Medical PressPatient Preference and Adherence1177-889X2023-04-01Volume 1798399382874Factors Affecting Immunosuppressive Medication Adherence in Liver Transplant Recipients with Poor Adherence: A Qualitative StudyOzdemir Koken ZSezer Ceren REKarahan SAbbasoglu OZeliha Ozdemir Koken,1 Rana Elcin Sezer Ceren,1 Sabri Karahan,2 Osman Abbasoglu3 1Surgical Nursing Department, Hacettepe University Faculty of Nursing, Ankara, Turkiye; 2Surgical Nursing Department, Harran University, Faculty of Health Science, Sanliurfa, Turkiye; 3General Surgery Department, Hacettepe University Faculty of Medicine, Ankara, TurkiyeCorrespondence: Zeliha Ozdemir Koken, Surgical Nursing Department, Hacettepe University Faculty of Nursing, Ankara, Turkiye, Email zeliha.ozdemir@hacettepe.edu.trPurpose: Preserving graft functions and preventing rejection is closely related to immunosuppressive medication adherence in liver transplant recipients. Therefore, it is essential to determine factors affecting immunosuppressive medication use positively or negatively in liver transplant recipients. This study aimed to explore the use of immunosuppressive medication experience in liver transplant recipients with poor adherence and reveal the factors affecting the medication adherence.Material and Methods: The study was conducted as a qualitative study with phenomenological approach. Seven adult liver transplant recipients were included in this study, who had poor adherence to immunosuppressive medication. Data was collected via in-depth personal interviews. Data analysis was conducted through inductive content analysis with three steps of preparation, organization, and reporting phases.Results: Content analysis revealed four main categories, nine categories and 31 sub-categories. Four main categories emerged from the interview data: medication adherence perception, types of medication non-adherence, factors affecting medication adherence negatively and factors affecting medication adherence positively.Conclusion: This study explored that there are several factors affecting immunosuppressive medication adherence among liver transplant recipients, both positively and negatively. In order to achieve liver transplant recipients’ total adherence to immunosuppressive medication, the factors affecting medication adherence positively and negatively should be understood. The study results are expected to contribute developing strategies to improve immunosuppressive medication adherence in liver transplant recipients.Keywords: immunosuppressive, liver transplant, medication adherence, medication non-adherencehttps://www.dovepress.com/factors-affecting-immunosuppressive-medication-adherence-in-liver-tran-peer-reviewed-fulltext-article-PPAimmunosuppressiveliver transplantmedication adherencemedication non-adherence |
| spellingShingle | Ozdemir Koken Z Sezer Ceren RE Karahan S Abbasoglu O Factors Affecting Immunosuppressive Medication Adherence in Liver Transplant Recipients with Poor Adherence: A Qualitative Study Patient Preference and Adherence immunosuppressive liver transplant medication adherence medication non-adherence |
| title | Factors Affecting Immunosuppressive Medication Adherence in Liver Transplant Recipients with Poor Adherence: A Qualitative Study |
| title_full | Factors Affecting Immunosuppressive Medication Adherence in Liver Transplant Recipients with Poor Adherence: A Qualitative Study |
| title_fullStr | Factors Affecting Immunosuppressive Medication Adherence in Liver Transplant Recipients with Poor Adherence: A Qualitative Study |
| title_full_unstemmed | Factors Affecting Immunosuppressive Medication Adherence in Liver Transplant Recipients with Poor Adherence: A Qualitative Study |
| title_short | Factors Affecting Immunosuppressive Medication Adherence in Liver Transplant Recipients with Poor Adherence: A Qualitative Study |
| title_sort | factors affecting immunosuppressive medication adherence in liver transplant recipients with poor adherence a qualitative study |
| topic | immunosuppressive liver transplant medication adherence medication non-adherence |
| url | https://www.dovepress.com/factors-affecting-immunosuppressive-medication-adherence-in-liver-tran-peer-reviewed-fulltext-article-PPA |
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