Betulin is a potent anti-tumor agent that is enhanced by cholesterol.

Betulin is a potent anti-tumor agent that is enhanced by cholesterol.

Betulinic Acid (BetA) and its derivatives have been extensively studied in the past for their anti-tumor effects, but relatively little is known about its precursor Betulin (BE). We found that BE induces apoptosis utilizing a similar mechanism as BetA and is prevented by cyclosporin A (CsA). BE indu...

Full description

Bibliographic Details
Main Authors: Franziska B Mullauer, Jan H Kessler, Jan Paul Medema
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2671171?pdf=render

Similar Items

Similar Items