Incorporation of porcine adenovirus 4 fiber protein enhances infectivity of adenovirus vector on dendritic cells: implications for immune-mediated cancer therapy.

Incorporation of porcine adenovirus 4 fiber protein enhances infectivity of adenovirus vector on dendritic cells: implications for immune-mediated cancer therapy.

One strategy in cancer immunotherapy is to capitalize on the key immunoregulatory and antigen presenting capabilities of dendritic cells (DCs). This approach is dependent on efficient delivery of tumor specific antigens to DCs, which subsequently induce an anti-tumor T-cell mediated immune response....

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Bibliographic Details
Main Authors: Ivy Wilkinson-Ryan, Julius Kim, Sojung Kim, Ferhat Ak, Lindzy Dodson, Marco Colonna, Matthew Powell, David Mutch, Dirk Spitzer, Ted Hansen, Simon P Goedegebuure, David Curiel, William Hawkins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4416912?pdf=render

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