Persulfate-Promoted Carbamoylation/Cyclization of Alkenes: Synthesis of Amide-Containing Quinazolinones

Persulfate-Promoted Carbamoylation/Cyclization of Alkenes: Synthesis of Amide-Containing Quinazolinones

The incorporation of amide groups into biologically active molecules has been proven to be an efficient strategy for drug design and discovery. In this study, we present a simple and practical method for the synthesis of amide-containing quinazolin-4(3<i>H</i>)-ones under transition-meta...

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Bibliographic Details
Main Authors: Jia-Jun Tang, Meng-Yang Zhao, Ying-Jun Lin, Li-Hua Yang, Long-Yong Xie
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Molecules
Subjects:
radical reaction
cascade cyclization
radical
quinazolinones
metal-free
Online Access:https://www.mdpi.com/1420-3049/29/5/997

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