Ischemic Preconditioning Provides Neuroprotection by Inhibiting NLRP3 Inflammasome Activation and Cell Pyroptosis

Ischemic Preconditioning Provides Neuroprotection by Inhibiting NLRP3 Inflammasome Activation and Cell Pyroptosis

Increasing evidence has demonstrated that ischemic preconditioning (IPC) increases cerebral tolerance to subsequent prolonged ischemic insults. However, the exact mechanisms underlying the process have not been fully explored. In the current study, we aim to investigate whether NLRP3 inflammasome an...

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Bibliographic Details
Main Authors: Li Gao, Xin Sun, Meibo Pan, Wenrui Zhang, Desheng Zhu, Zhongjiao Lu, Kan Wang, Yinfeng Dong, Yangtai Guan
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Brain Sciences
Subjects:
ischemic preconditioning (IPC)
NLRP3 inflammasome
pyroptosis
ischemic stroke
neuroprotection
Online Access:https://www.mdpi.com/2076-3425/13/6/897

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