<named-content content-type="genus-species">Burkholderia pseudomallei</named-content> Δ<italic toggle="yes">tonB</italic> Δ<italic toggle="yes">hcp1</italic> Live Attenuated Vaccine Strain Elicits Full Protective Immunity against Aerosolized Melioidosis Infection

<named-content content-type="genus-species">Burkholderia pseudomallei</named-content> Δ<italic toggle="yes">tonB</italic> Δ<italic toggle="yes">hcp1</italic> Live Attenuated Vaccine Strain Elicits Full Protective Immunity against Aerosolized Melioidosis Infection

ABSTRACT Burkholderia pseudomallei is a Gram-negative facultative intracellular bacterium and the causative agent of melioidosis, a severe infectious disease found throughout the tropics. This organism is closely related to Burkholderia mallei, the etiological agent of glanders disease which primari...

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Bibliographic Details
Main Authors: Nittaya Khakhum, Preeti Bharaj, Julia N. Myers, Daniel Tapia, Paul B. Kilgore, Brittany N. Ross, David H. Walker, Janice J. Endsley, Alfredo G. Torres
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mSphere
Subjects:
Burkholderia pseudomallei
melioidosis
live attenuated vaccine
tonB
hcp1
Th17
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00570-18

Internet

https://journals.asm.org/doi/10.1128/mSphere.00570-18

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