Nanoparticles in Ocular Drug Delivery Systems
Conventional ophthalmic formulations lack a prolonged drug release effect and mucoadhesive properties, decreasing their residence time in the precorneal area and, therefore, in drug penetration across ocular tissues, presenting low bioavailability with a consequent reduction in therapeutic efficacy...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-06-01
|
Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/15/6/1675 |
_version_ | 1797593087900385280 |
---|---|
author | Hugo Almeida Ana Catarina Silva |
author_facet | Hugo Almeida Ana Catarina Silva |
author_sort | Hugo Almeida |
collection | DOAJ |
description | Conventional ophthalmic formulations lack a prolonged drug release effect and mucoadhesive properties, decreasing their residence time in the precorneal area and, therefore, in drug penetration across ocular tissues, presenting low bioavailability with a consequent reduction in therapeutic efficacy [...] |
first_indexed | 2024-03-11T02:03:48Z |
format | Article |
id | doaj.art-ffbbc0667cf847bbb81835eedd0960df |
institution | Directory Open Access Journal |
issn | 1999-4923 |
language | English |
last_indexed | 2024-03-11T02:03:48Z |
publishDate | 2023-06-01 |
publisher | MDPI AG |
record_format | Article |
series | Pharmaceutics |
spelling | doaj.art-ffbbc0667cf847bbb81835eedd0960df2023-11-18T12:04:53ZengMDPI AGPharmaceutics1999-49232023-06-01156167510.3390/pharmaceutics15061675Nanoparticles in Ocular Drug Delivery SystemsHugo Almeida0Ana Catarina Silva1UCIBIO (Research Unit on Applied Molecular Biosciences), REQUIMTE (Rede de Química e Tecnologia), MEDTECH (Medicines and Healthcare Products), Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, PortugalUCIBIO (Research Unit on Applied Molecular Biosciences), REQUIMTE (Rede de Química e Tecnologia), MEDTECH (Medicines and Healthcare Products), Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, PortugalConventional ophthalmic formulations lack a prolonged drug release effect and mucoadhesive properties, decreasing their residence time in the precorneal area and, therefore, in drug penetration across ocular tissues, presenting low bioavailability with a consequent reduction in therapeutic efficacy [...]https://www.mdpi.com/1999-4923/15/6/1675n/a |
spellingShingle | Hugo Almeida Ana Catarina Silva Nanoparticles in Ocular Drug Delivery Systems Pharmaceutics n/a |
title | Nanoparticles in Ocular Drug Delivery Systems |
title_full | Nanoparticles in Ocular Drug Delivery Systems |
title_fullStr | Nanoparticles in Ocular Drug Delivery Systems |
title_full_unstemmed | Nanoparticles in Ocular Drug Delivery Systems |
title_short | Nanoparticles in Ocular Drug Delivery Systems |
title_sort | nanoparticles in ocular drug delivery systems |
topic | n/a |
url | https://www.mdpi.com/1999-4923/15/6/1675 |
work_keys_str_mv | AT hugoalmeida nanoparticlesinoculardrugdeliverysystems AT anacatarinasilva nanoparticlesinoculardrugdeliverysystems |