Nanoparticles in Ocular Drug Delivery Systems

Conventional ophthalmic formulations lack a prolonged drug release effect and mucoadhesive properties, decreasing their residence time in the precorneal area and, therefore, in drug penetration across ocular tissues, presenting low bioavailability with a consequent reduction in therapeutic efficacy...

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Main Authors: Hugo Almeida, Ana Catarina Silva
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pharmaceutics
Subjects:
n/a
Online Access:https://www.mdpi.com/1999-4923/15/6/1675
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author Hugo Almeida
Ana Catarina Silva
author_facet Hugo Almeida
Ana Catarina Silva
author_sort Hugo Almeida
collection DOAJ
description Conventional ophthalmic formulations lack a prolonged drug release effect and mucoadhesive properties, decreasing their residence time in the precorneal area and, therefore, in drug penetration across ocular tissues, presenting low bioavailability with a consequent reduction in therapeutic efficacy [...]
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spelling doaj.art-ffbbc0667cf847bbb81835eedd0960df2023-11-18T12:04:53ZengMDPI AGPharmaceutics1999-49232023-06-01156167510.3390/pharmaceutics15061675Nanoparticles in Ocular Drug Delivery SystemsHugo Almeida0Ana Catarina Silva1UCIBIO (Research Unit on Applied Molecular Biosciences), REQUIMTE (Rede de Química e Tecnologia), MEDTECH (Medicines and Healthcare Products), Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, PortugalUCIBIO (Research Unit on Applied Molecular Biosciences), REQUIMTE (Rede de Química e Tecnologia), MEDTECH (Medicines and Healthcare Products), Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, PortugalConventional ophthalmic formulations lack a prolonged drug release effect and mucoadhesive properties, decreasing their residence time in the precorneal area and, therefore, in drug penetration across ocular tissues, presenting low bioavailability with a consequent reduction in therapeutic efficacy [...]https://www.mdpi.com/1999-4923/15/6/1675n/a
spellingShingle Hugo Almeida
Ana Catarina Silva
Nanoparticles in Ocular Drug Delivery Systems
Pharmaceutics
n/a
title Nanoparticles in Ocular Drug Delivery Systems
title_full Nanoparticles in Ocular Drug Delivery Systems
title_fullStr Nanoparticles in Ocular Drug Delivery Systems
title_full_unstemmed Nanoparticles in Ocular Drug Delivery Systems
title_short Nanoparticles in Ocular Drug Delivery Systems
title_sort nanoparticles in ocular drug delivery systems
topic n/a
url https://www.mdpi.com/1999-4923/15/6/1675
work_keys_str_mv AT hugoalmeida nanoparticlesinoculardrugdeliverysystems
AT anacatarinasilva nanoparticlesinoculardrugdeliverysystems