XDec-CHI reveals immunosuppressive interactions in pancreatic ductal adenocarcinoma

Summary: Most cancers harbor a diverse collection of cell types including a typically heterogeneous cancer cell fraction. To reconstruct cell-intrinsic and heterotypic interactions driving tumor progression, we combine the XDec deconvolution method with cell-type-specific gene expression correlation...

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Bibliographic Details
Main Authors: Emily L. LaPlante, Dongliang Liu, Varduhi Petrosyan, Qizhi Yao, Aleksandar Milosavljevic
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222015218