A large size-selective DNA nanopore with sensing applications
Artificial nanopores can perform selective gating of molecules analogous to transmembrane proteins. Here, the authors design a DNA origami pore with a controllable lid for size-selective gating and translocation of macromolecules and evaluate its biosensing properties by single particle assay.
Bibliographic Details
| Main Authors: |
Rasmus P. Thomsen,
Mette Galsgaard Malle,
Anders Hauge Okholm,
Swati Krishnan,
Søren S.-R. Bohr,
Rasmus Schøler Sørensen,
Oliver Ries,
Stefan Vogel,
Friedrich C. Simmel,
Nikos S. Hatzakis,
Jørgen Kjems |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2019-12-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-019-13284-1
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