FXR-mediated inhibition of autophagy contributes to FA-induced TG accumulation and accordingly reduces FA-induced lipotoxicity
Abstract Background Excessive dietary fat intake induces lipid deposition and contributes to the progress of nonalcoholic fatty liver disease (NAFLD). However, the underlying mechanisms are still unclear. Methods Yellow catfish were given two experimental diets with dietary lipid levels of 11.3 and...
Main Authors: | Kun Wu, Tao Zhao, Christer Hogstrand, Yi-Chuang Xu, Shi-Cheng Ling, Guang-Hui Chen, Zhi Luo |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-03-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12964-020-0525-1 |
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