Gastric Cancer and Gastric Microbiome
Gastric cancer remains a significant disease burden in Korea, with Helicobacter pylori infections being the most crucial risk factor. With the advent of next-generation sequencing, the role of gastric microbiota in gastric cancer has attracted increasing attention. Studies have shown that the gastri...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Jin Publishing & Printing Co.
2023-05-01
|
| Series: | The Korean Journal of Gastroenterology |
| Subjects: | |
| Online Access: | https://www.kjg.or.kr/journal/view.html?uid=5924&vmd=Full |
| _version_ | 1797263504509501440 |
|---|---|
| author | Hyo-Joon Yang |
| author_facet | Hyo-Joon Yang |
| author_sort | Hyo-Joon Yang |
| collection | DOAJ |
| description | Gastric cancer remains a significant disease burden in Korea, with Helicobacter pylori infections being the most crucial risk factor. With the advent of next-generation sequencing, the role of gastric microbiota in gastric cancer has attracted increasing attention. Studies have shown that the gastric microbiota of patients with gastric cancer differs in composition from that of the controls, with reduced microbial diversity. Lactic acid bacteria and oral microflora are often enriched in gastric cancer and are believed to induce chronic inflammation or promote the production of nitroso compounds. This review focuses on recent studies comparing the gastric microbiome in gastric cancer patients and controls. |
| first_indexed | 2024-04-25T00:14:04Z |
| format | Article |
| id | doaj.art-ffc25fe2da4e420eaed23e9d94bc4ea4 |
| institution | Directory Open Access Journal |
| issn | 1598-9992 2233-6869 |
| language | English |
| last_indexed | 2024-04-25T00:14:04Z |
| publishDate | 2023-05-01 |
| publisher | Jin Publishing & Printing Co. |
| record_format | Article |
| series | The Korean Journal of Gastroenterology |
| spelling | doaj.art-ffc25fe2da4e420eaed23e9d94bc4ea42024-03-13T07:00:25ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692023-05-0181523524210.4166/kjg.2023.055Gastric Cancer and Gastric MicrobiomeHyo-Joon Yang0https://orcid.org/0000-0002-0265-672XDivision of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, KoreaGastric cancer remains a significant disease burden in Korea, with Helicobacter pylori infections being the most crucial risk factor. With the advent of next-generation sequencing, the role of gastric microbiota in gastric cancer has attracted increasing attention. Studies have shown that the gastric microbiota of patients with gastric cancer differs in composition from that of the controls, with reduced microbial diversity. Lactic acid bacteria and oral microflora are often enriched in gastric cancer and are believed to induce chronic inflammation or promote the production of nitroso compounds. This review focuses on recent studies comparing the gastric microbiome in gastric cancer patients and controls.https://www.kjg.or.kr/journal/view.html?uid=5924&vmd=Fullgastric cancergastric microbiomehelicobacter pylori16s rrna |
| spellingShingle | Hyo-Joon Yang Gastric Cancer and Gastric Microbiome The Korean Journal of Gastroenterology gastric cancer gastric microbiome helicobacter pylori 16s rrna |
| title | Gastric Cancer and Gastric Microbiome |
| title_full | Gastric Cancer and Gastric Microbiome |
| title_fullStr | Gastric Cancer and Gastric Microbiome |
| title_full_unstemmed | Gastric Cancer and Gastric Microbiome |
| title_short | Gastric Cancer and Gastric Microbiome |
| title_sort | gastric cancer and gastric microbiome |
| topic | gastric cancer gastric microbiome helicobacter pylori 16s rrna |
| url | https://www.kjg.or.kr/journal/view.html?uid=5924&vmd=Full |
| work_keys_str_mv | AT hyojoonyang gastriccancerandgastricmicrobiome |