Development and Validation of RP-HPLC Method for the Determination of Adefovir Dipivoxil in Bulk and in Pharmaceutical Formulation

Development and Validation of RP-HPLC Method for the Determination of Adefovir Dipivoxil in Bulk and in Pharmaceutical Formulation

A rapid and sensitive RP-HPLC method with UV detection (262 nm) for routine analysis of adefovir dipivoxil in bulk and in pharmaceutical formulation was developed. Chromatography was performed with mobile phase containing a mixture of acetonitrile and phosphate buffer (50:50, v/v) with flow rate 1.0...

Full description

Bibliographic Details
Main Authors:	Zaheer Ahmed, B. Gopinath, A. Sathish Kumar Shetty, B. K. Sridhar
Format:	Article
Language:	English
Published:	Hindawi Limited 2009-01-01
Series:	E-Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2009/157868

Similar Items

Adefovir Dipivoxil
by: Francisco Javier Hevia-Urrutia
Published: (2008-11-01)

Optimization and validation of an RP-HPLC method for the estimation of 6-mercaptopurine in bulk and pharmaceutical formulations
by: Vanita Somasekhar
Published: (2014-12-01)

Stability-indicating RP-HPLC method development and validation for estimation of Mupirocin calcium in bulk and in pharmaceutical formulation
by: Durgeshwari J. Kalal, et al.
Published: (2022-03-01)

Long-term therapy with adefovir dipivoxil for HBeAg positive chronic hepatitis B patients with various baseline biochemical levels: Results from 4 years adefovir dipivoxil treatment
by: L. Zhuang, et al.
Published: (2014-04-01)

Simultaneous RP-HPLC determination of sparfloxacin and dexamethasone in pharmaceutical formulations
by: Syed Naeem Razzaq, et al.
Published: (2013-06-01)

Effect of Adefovir Dipivoxil on the Inhibition of Osteogenic Differentiation of Mesenchymal Stem Cells and Osteoblasts
by: Ho PARK
Published: (2023-12-01)

Melting Diagrams of Adefovir Dipivoxil and Dicarboxylic Acids: An Approach to Assess Cocrystal Compositions
by: Hyunseon An, et al.
Published: (2019-01-01)

Adefovir dipivoxil inhibits APL progression through degradation of the oncoprotein PML-RARA
by: Xubo Gong, et al.
Published: (2022-11-01)

Fanconi syndrome induced by adefovir dipivoxil: a case report and clinical review
by: Kaixin Song, et al.
Published: (2020-10-01)

Development and validation of RP HPLC method for determination of metformin and sitagliptin in bulk and pharmaceutical dosage form
by: Kavitha D., et al.
Published: (2017-04-01)

Clinical features of hypophosphatemic osteomalacia induced by long-term low-dose adefovir dipivoxil
by: Zhu S, et al.
Published: (2017-12-01)

Development and validation of RP-HPLC method for the estimation of Erlotinib in pharmaceutical formulation
by: S.T. Latha, et al.
Published: (2017-02-01)

Low-dose adefovir dipivoxil–induced hypophosphatemia osteomalacia in five chronic hepatitis B virus–infected patients. Is low-dose adefovir dipivoxil–induced nephrotoxicity completely reversible?
by: Qian YY, et al.
Published: (2019-04-01)

Adefovir dipivoxil induces DNA replication stress and augments ATR inhibitor-related cytotoxicity
by: Patel, A, et al.
Published: (2020)

Stability Indicating RP-HPLC Method Development and Validation for Bosentan in Pharmaceutical Formulations
by: Mehmet Emrah YAMAN, et al.
Published: (2022-05-01)

A validated RP-HPLC method for simultaneous determination of propranolol and valsartan in bulk drug and gel formulation
by: Syed Sarim Imam, et al.
Published: (2013-01-01)

A randomized placebo-controlled trial of adefovir dipivoxil in advanced HIV infection: the ADHOC trial.
by: ADHOC International Steering Committee
Published: (2002)

Meta-analysis: Adefovir dipivoxil in combination with lamivudine in patients with lamivudine-resistant hepatitis B virus
by: Wang Li-Chun, et al.
Published: (2009-10-01)

Development and Validation of an RP-HPLC-PDA Method for Determination of Paracetamol, Caffeine and Tramadol Hydrochloride in Pharmaceutical Formulations
by: Fernando J. Pereira, et al.
Published: (2021-05-01)

Eficácia do adefovir dipivoxil, entecavir e telbivudina para o tratamento da hepatite crônica B: revisão sistemática The efficacy of adefovir dipivoxil, entecavir and telbivudine for chronic hepatitis B treatment: a systematic review
by: Alessandra Maciel Almeida, et al.
Published: (2010-08-01)

RP-HPLC-DAD method for the determination of phenylepherine, paracetamol, caffeine and chlorpheniramine in bulk and marketed formulation
by: A.P. Dewani, et al.
Published: (2014-11-01)

Optimized and Validated RP-UPLC Method for the Determination of Losartan Potassium and Chlorthalidone in Pharmaceutical Formulations
by: Tadiboyina Sirisha, et al.
Published: (2015-03-01)

Simultaneous determination of gemifloxacin and diuretics in bulk, pharmaceutical dosage forms and human serum by RP-HPLC
by: Najma Sultana, et al.
Published: (2010-01-01)

Adefovir dipivoxil nella terapia dell’epatite B cronica: profilo farmacologico clinico ed economico
by: Lorenzo Pradelli, et al.
Published: (2005-12-01)

Cost-effectiveness analysis of lamivudine, telbivudine, and entecavir in treatment of chronic hepatitis B with adefovir dipivoxil resistance
by: Wang G, et al.
Published: (2015-06-01)

Deep sequencing analysis of HBV genotype shift and correlation with antiviral efficiency during adefovir dipivoxil therapy.
by: Yuwei Wang, et al.
Published: (2015-01-01)

Development and validation of RP HPLC method for the estimation of Sofosbuvir and related impurity in bulk and pharmaceutical dosage form
by: Shiny Ganji, et al.
Published: (2021-07-01)

Design of experiment avenue for development and validation of RP-HPLC-PDA method for determination of apremilast in bulk and in in-house tablet formulation
by: Suraj R. Chaudhari, et al.
Published: (2019-02-01)

A Validated RP-HPLC Method for the Simultaneous Detection and Quantification of Pyridoxine and Terizidone in Pharmaceutical Formulations
by: Ngabo Yves Musafili, et al.
Published: (2021-12-01)

New stability indicating RP-HPLC-PDA method for determination of mifepristone in bulk and tablet formulation
by: Mohammad Mojeeb Gulzar Khan, et al.
Published: (2021-11-01)

Validation of a Cost-Effective RP-HPLC Method for Quantitative Investigation of Daclatasvir Dihydrochloride in Pharmaceutical Formulations
by: Sadaf Sarfraz, et al.
Published: (2023-01-01)

Adefovir Dipivoxil as a Therapeutic Candidate for Medullary Thyroid Carcinoma: Targeting RET and STAT3 Proto-Oncogenes
by: Tariq Alqahtani, et al.
Published: (2023-04-01)

Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report
by: Tanaka Motoyuki, et al.
Published: (2012-08-01)

Adefovir dipivoxil and pegylated interferon alpha for the treatment of chronic hepatitis B: an updated systematic review and economic evaluation
by: J Jones, et al.
Published: (2009-07-01)

RP-HPLC method development and validation for the estimation of Emtricitabine, Bictegravir and Tenofovir alafenamide in bulk and pharmaceutical dosage form
by: Tej Kumar Kokkirala, et al.
Published: (2019-12-01)

Gradient RP-HPLC method for the determination of potential impurities in dabigatran etexilate in bulk drug and capsule formulations
by: J. Nagadeep, et al.
Published: (2019-12-01)

Liquid-Assisted Grinding to Prepare a Cocrystal of Adefovir Dipivoxil Thermodynamically Less Stable than Its Neat Phase
by: Sungyup Jung, et al.
Published: (2015-11-01)

Adefovir dipivoxil-induced development of osteomalacia and Fanconi syndrome during the treatment of hepatitis B virus (HBV)-related cirrhosis
by: Orietta Staltari, et al.
Published: (2014-12-01)

Adefovir dipivoxil induced hypophosphatemic osteomalacia in chronic hepatitis B: a comparative study of Chinese and foreign case series
by: Nan Chen, et al.
Published: (2018-05-01)

Development and validation of stability indicating RP-HPLC and HPTLC for determination of Niclosamide in bulk and in synthetic mixture
by: C. Paghadar, et al.
Published: (2019-12-01)