Impact of Exogenous Treatment with Histidine on Hepatocellular Carcinoma Cells

Impact of Exogenous Treatment with Histidine on Hepatocellular Carcinoma Cells

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. Sorafenib, a multi-kinase inhibitor, is the first-line therapy for advanced HCC. However, long-term exposure to sorafenib often results in reduced sensitivity and the development of resistance. Although v...

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Bibliographic Details
Main Authors: Yusun Park, Yeonju Han, Dongwoo Kim, Sua Cho, WonJin Kim, Hyemin Hwang, Hye Won Lee, Dai Hoon Han, Kyung Sik Kim, Mijin Yun, Misu Lee
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
hepatocellular carcinoma
sorafenib
cancer metabolism
histidine
drug sensitivity
Online Access:https://www.mdpi.com/2072-6694/14/5/1205

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