TREM2 mediates physical exercise-promoted neural functional recovery in rats with ischemic stroke via microglia-promoted white matter repair

TREM2 mediates physical exercise-promoted neural functional recovery in rats with ischemic stroke via microglia-promoted white matter repair

Abstract Background The repair of white matter injury is of significant importance for functional recovery after ischemic stroke, and the up-regulation of triggering receptors expressed on myeloid cells 2 (TREM2) after ischemic stroke is neuroprotective and implicated in remyelination. However, the...

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Bibliographic Details
Main Authors: Jinghui Xu, Liying Zhang, Mingyue Li, Xiaofei He, Jing Luo, Rui Wu, Zhongqiu Hong, Haiqing Zheng, Xiquan Hu
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Neuroinflammation
Subjects:
Ischemic stroke
Physical exercise
Triggering receptor expressed on myeloid cells 2
Brain white matter repair
Microglia
Online Access:https://doi.org/10.1186/s12974-023-02741-w

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