Erythropoietin alleviates lung ischemia-reperfusion injury by activating the FGF23/FGFR4/ERK signaling pathway

Erythropoietin alleviates lung ischemia-reperfusion injury by activating the FGF23/FGFR4/ERK signaling pathway

Background The purpose of the present study was to investigate the effect of erythropoietin (EPO) on lung ischemia-reperfusion injury (LIRI). Methods Sprague Dawley rats and BEAS-2B cells were employed to construct an ischemia-reperfusion (I/R)-induced model in vivo and in vitro, respectively. After...

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Bibliographic Details
Main Authors: Xiaosheng Jin, Weijing Jin, Guoping Li, Jisheng Zheng, Xianrong Xu
Format: Article
Language:English
Published: PeerJ Inc. 2024-03-01
Series:PeerJ
Subjects:
Erythropoietin
Lung ischemia-reperfusion injury
FGF23
Online Access:https://peerj.com/articles/17123.pdf

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