Zika Virus Circulation in Mali
The circulation of Zika virus (ZIKV) in Mali has not been clearly characterized. Therefore, we conducted a serologic survey of 793 asymptomatic volunteers >15 years of age (2016), and 637 blood donors (2013) to assess the seroprevalence of ZIKV infection in 2 ecoclimatic regions of Mali, tropical...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2020-05-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/26/5/19-1383_article |
| _version_ | 1818041467832107008 |
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| author | Issa Diarra Elif Nurtop Abdoul Karim Sangaré Issaka Sagara Boris Pastorino Souleymane Sacko Amatigué Zeguimé Drissa Coulibaly Bakary Fofana Pierre Gallian Stephane Priet Jan Felix Drexler Anna-Bella Failloux Abdoulaye Dabo Mahamadou Ali Thera Abdoulaye Djimdé Bourèma Kouriba Simon Cauchemez Xavier de Lamballerie Nathanaël Hozé Ogobara K. Doumbo |
| author_facet | Issa Diarra Elif Nurtop Abdoul Karim Sangaré Issaka Sagara Boris Pastorino Souleymane Sacko Amatigué Zeguimé Drissa Coulibaly Bakary Fofana Pierre Gallian Stephane Priet Jan Felix Drexler Anna-Bella Failloux Abdoulaye Dabo Mahamadou Ali Thera Abdoulaye Djimdé Bourèma Kouriba Simon Cauchemez Xavier de Lamballerie Nathanaël Hozé Ogobara K. Doumbo |
| author_sort | Issa Diarra |
| collection | DOAJ |
| description | The circulation of Zika virus (ZIKV) in Mali has not been clearly characterized. Therefore, we conducted a serologic survey of 793 asymptomatic volunteers >15 years of age (2016), and 637 blood donors (2013) to assess the seroprevalence of ZIKV infection in 2 ecoclimatic regions of Mali, tropical savannah and warm semiarid region, using ELISA and seroneutralization assays. The overall seroprevalence was ≈12% and increased with age, with no statistical difference between male and female participants. In the warm semiarid study sites we detected immunological markers of an outbreak that occurred in the late 1990s in 18% (95% CI 13%–23%) of participants. In tropical savannah sites, we estimated a low rate of endemic transmission, with 2.5% (95% CI 2.0%–3.1%) of population infected by ZIKV annually. These data demonstrate the circulation of ZIKV in Mali and provide evidence of a previously unidentified outbreak that occurred in the late 1990s. |
| first_indexed | 2024-12-10T08:30:54Z |
| format | Article |
| id | doaj.art-ffc646bd71694816b08dc485e4769a01 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-10T08:30:54Z |
| publishDate | 2020-05-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-ffc646bd71694816b08dc485e4769a012022-12-22T01:56:06ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592020-05-0126594595210.3201/eid2605.191383Zika Virus Circulation in MaliIssa DiarraElif NurtopAbdoul Karim SangaréIssaka SagaraBoris PastorinoSouleymane SackoAmatigué ZeguiméDrissa CoulibalyBakary FofanaPierre GallianStephane PrietJan Felix DrexlerAnna-Bella FaillouxAbdoulaye DaboMahamadou Ali TheraAbdoulaye DjimdéBourèma KouribaSimon CauchemezXavier de LamballerieNathanaël HozéOgobara K. DoumboThe circulation of Zika virus (ZIKV) in Mali has not been clearly characterized. Therefore, we conducted a serologic survey of 793 asymptomatic volunteers >15 years of age (2016), and 637 blood donors (2013) to assess the seroprevalence of ZIKV infection in 2 ecoclimatic regions of Mali, tropical savannah and warm semiarid region, using ELISA and seroneutralization assays. The overall seroprevalence was ≈12% and increased with age, with no statistical difference between male and female participants. In the warm semiarid study sites we detected immunological markers of an outbreak that occurred in the late 1990s in 18% (95% CI 13%–23%) of participants. In tropical savannah sites, we estimated a low rate of endemic transmission, with 2.5% (95% CI 2.0%–3.1%) of population infected by ZIKV annually. These data demonstrate the circulation of ZIKV in Mali and provide evidence of a previously unidentified outbreak that occurred in the late 1990s.https://wwwnc.cdc.gov/eid/article/26/5/19-1383_articleZika virusseroprevalenceMalivirusesarbovirusvector-borne infections |
| spellingShingle | Issa Diarra Elif Nurtop Abdoul Karim Sangaré Issaka Sagara Boris Pastorino Souleymane Sacko Amatigué Zeguimé Drissa Coulibaly Bakary Fofana Pierre Gallian Stephane Priet Jan Felix Drexler Anna-Bella Failloux Abdoulaye Dabo Mahamadou Ali Thera Abdoulaye Djimdé Bourèma Kouriba Simon Cauchemez Xavier de Lamballerie Nathanaël Hozé Ogobara K. Doumbo Zika Virus Circulation in Mali Emerging Infectious Diseases Zika virus seroprevalence Mali viruses arbovirus vector-borne infections |
| title | Zika Virus Circulation in Mali |
| title_full | Zika Virus Circulation in Mali |
| title_fullStr | Zika Virus Circulation in Mali |
| title_full_unstemmed | Zika Virus Circulation in Mali |
| title_short | Zika Virus Circulation in Mali |
| title_sort | zika virus circulation in mali |
| topic | Zika virus seroprevalence Mali viruses arbovirus vector-borne infections |
| url | https://wwwnc.cdc.gov/eid/article/26/5/19-1383_article |
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