Cerebral proliferative angiopathy depicted by four-dimensional computed tomographic angiography: A case report
Cerebral proliferative angiopathy is a rare cerebrovascular disorder characterized by diffuse abnormal vessels with intermingled brain parenchyma fed by many arteries and draining into many veins without high-flow arteriovenous shunts, which is usually confirmed by conventional digital subtraction a...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-07-01
|
| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043322002783 |
| _version_ | 1818212256284934144 |
|---|---|
| author | Shuichi Ito, MD Mitsunori Kanagaki, MD, PhD Naoya Yoshimoto, MD Yoichiro Hijikata, MD Marina Shimizu, MD Hiroyuki Kimura, MD, PhD |
| author_facet | Shuichi Ito, MD Mitsunori Kanagaki, MD, PhD Naoya Yoshimoto, MD Yoichiro Hijikata, MD Marina Shimizu, MD Hiroyuki Kimura, MD, PhD |
| author_sort | Shuichi Ito, MD |
| collection | DOAJ |
| description | Cerebral proliferative angiopathy is a rare cerebrovascular disorder characterized by diffuse abnormal vessels with intermingled brain parenchyma fed by many arteries and draining into many veins without high-flow arteriovenous shunts, which is usually confirmed by conventional digital subtraction angiography. However, dilution of the contrast medium due to the markedly increased blood flow and volume in cerebral proliferative angiopathy leads to low-contrast angiography. We report a 53-year-old man with cerebral proliferative angiopathy who underwent CT, MR imaging, MR angiography, digital subtraction angiography and 4D-CTA. The 4D-CTA exhibited abnormal vessels without early venous filling between the atrophic brain parenchyma in higher contrast than the angiography due to high spatial and time resolution, whereas the left external carotid angiography visualized the characteristic transdural supply more clearly than the 4D-CTA due to high vascular selectivity. Therefore, novel 4D-CTA and conventional angiography plays a complementary role in the accurate diagnosis of cerebral proliferative angiopathy. Taking invasiveness into account, 4D-CTA may be advantageous for the diagnosis of cerebral proliferative angiopathy based on the characteristic imaging findings. |
| first_indexed | 2024-12-12T05:45:30Z |
| format | Article |
| id | doaj.art-ffcb4802188446b4b57ed0ae14eb833a |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-12T05:45:30Z |
| publishDate | 2022-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-ffcb4802188446b4b57ed0ae14eb833a2022-12-22T00:35:49ZengElsevierRadiology Case Reports1930-04332022-07-0117723322336Cerebral proliferative angiopathy depicted by four-dimensional computed tomographic angiography: A case reportShuichi Ito, MD0Mitsunori Kanagaki, MD, PhD1Naoya Yoshimoto, MD2Yoichiro Hijikata, MD3Marina Shimizu, MD4Hiroyuki Kimura, MD, PhD5Department of Diagnostic Radiology, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan; Corresponding authorDepartment of Diagnostic Radiology, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, JapanDepartment of Neurosurgery, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, JapanDepartment of Diagnostic Radiology, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, JapanDepartment of Diagnostic Radiology, Japanese Red Cross Wakayama Medical Center, Wakayama, JapanDepartment of Diagnostic Radiology, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, JapanCerebral proliferative angiopathy is a rare cerebrovascular disorder characterized by diffuse abnormal vessels with intermingled brain parenchyma fed by many arteries and draining into many veins without high-flow arteriovenous shunts, which is usually confirmed by conventional digital subtraction angiography. However, dilution of the contrast medium due to the markedly increased blood flow and volume in cerebral proliferative angiopathy leads to low-contrast angiography. We report a 53-year-old man with cerebral proliferative angiopathy who underwent CT, MR imaging, MR angiography, digital subtraction angiography and 4D-CTA. The 4D-CTA exhibited abnormal vessels without early venous filling between the atrophic brain parenchyma in higher contrast than the angiography due to high spatial and time resolution, whereas the left external carotid angiography visualized the characteristic transdural supply more clearly than the 4D-CTA due to high vascular selectivity. Therefore, novel 4D-CTA and conventional angiography plays a complementary role in the accurate diagnosis of cerebral proliferative angiopathy. Taking invasiveness into account, 4D-CTA may be advantageous for the diagnosis of cerebral proliferative angiopathy based on the characteristic imaging findings.http://www.sciencedirect.com/science/article/pii/S1930043322002783Cerebral proliferative angiopathy4D-CTAFour-dimensional computed tomographic angiographyTime-resolved CT angiographyDSADigital subtraction angiography |
| spellingShingle | Shuichi Ito, MD Mitsunori Kanagaki, MD, PhD Naoya Yoshimoto, MD Yoichiro Hijikata, MD Marina Shimizu, MD Hiroyuki Kimura, MD, PhD Cerebral proliferative angiopathy depicted by four-dimensional computed tomographic angiography: A case report Radiology Case Reports Cerebral proliferative angiopathy 4D-CTA Four-dimensional computed tomographic angiography Time-resolved CT angiography DSA Digital subtraction angiography |
| title | Cerebral proliferative angiopathy depicted by four-dimensional computed tomographic angiography: A case report |
| title_full | Cerebral proliferative angiopathy depicted by four-dimensional computed tomographic angiography: A case report |
| title_fullStr | Cerebral proliferative angiopathy depicted by four-dimensional computed tomographic angiography: A case report |
| title_full_unstemmed | Cerebral proliferative angiopathy depicted by four-dimensional computed tomographic angiography: A case report |
| title_short | Cerebral proliferative angiopathy depicted by four-dimensional computed tomographic angiography: A case report |
| title_sort | cerebral proliferative angiopathy depicted by four dimensional computed tomographic angiography a case report |
| topic | Cerebral proliferative angiopathy 4D-CTA Four-dimensional computed tomographic angiography Time-resolved CT angiography DSA Digital subtraction angiography |
| url | http://www.sciencedirect.com/science/article/pii/S1930043322002783 |
| work_keys_str_mv | AT shuichiitomd cerebralproliferativeangiopathydepictedbyfourdimensionalcomputedtomographicangiographyacasereport AT mitsunorikanagakimdphd cerebralproliferativeangiopathydepictedbyfourdimensionalcomputedtomographicangiographyacasereport AT naoyayoshimotomd cerebralproliferativeangiopathydepictedbyfourdimensionalcomputedtomographicangiographyacasereport AT yoichirohijikatamd cerebralproliferativeangiopathydepictedbyfourdimensionalcomputedtomographicangiographyacasereport AT marinashimizumd cerebralproliferativeangiopathydepictedbyfourdimensionalcomputedtomographicangiographyacasereport AT hiroyukikimuramdphd cerebralproliferativeangiopathydepictedbyfourdimensionalcomputedtomographicangiographyacasereport |