Metformin promotes anticancer activity of NK cells in a p38 MAPK dependent manner

Metformin promotes anticancer activity of NK cells in a p38 MAPK dependent manner

Metformin, a drug prescribed to treat type 2 diabetes, has been reported to possess antitumor activity via immunity activation. However, the influence of metformin on natural killer (NK) cells is not fully understood. Here, we investigated whether metformin exerts a potent anticancer effect by activ...

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Bibliographic Details
Main Authors: Wenjiao Xia, Xin Qi, Mingfeng Li, Yu Wu, Lulu Sun, Xinglong Fan, Yuan Yuan, Jing Li
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
metformin
nk cells
cancer surveillance
immunotherapy
p38 mapk
Online Access:http://dx.doi.org/10.1080/2162402X.2021.1995999

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