Effect of Obesity and Roux-En-Y Gastric Surgery on Omeprazole Pharmacokinetics

Effect of Obesity and Roux-En-Y Gastric Surgery on Omeprazole Pharmacokinetics

Introduction: The prevalence of obesity is increasing globally. The principal aim was to evaluate whether gastric bypass surgery modifies the bioavailability and pharmacokinetic (PK) parameters of omeprazole. Methods: Controlled, open-label, bioavailability clinical trial in patients undergoing Roux...

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Bibliographic Details
Main Authors: Antonio Portolés-Pérez, Ana Belén Rivas Paterna, Andrés Sánchez Pernaute, Antonio José Torres García, Carmen Moreno Lopera, Luis M. Chicharro, Fernando Bandrés, Amanda López-Picado, Miguel A. Rubio, Emilio Vargas Castrillón
Format: Article
Language:English
Published: Karger Publishers 2022-01-01
Series:Obesity Facts
Subjects:
bioavailability
pharmacokinetics-pharmacodynamics
bariatric surgery
omeprazole
obesity
Online Access:https://www.karger.com/Article/FullText/521570

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