Generation of a homozygous FIS1 knockout human embryonic stem cell line GIBHe015-B by CRISPR/Cas9 system
The mitochondrial fission protein 1 (FIS1) is essential for mitochondrial division or fission and has been determined to mediate mitochondrial and peroxisomal fission. Other studies also found that FIS1 functions as an essential component of the mitophagy and apoptosis pathways in mammalian cells, s...
Main Authors: | Mingquan Wang, Jun Tang, Tiancheng Zhou, Yuchan Mai, Yanling Zhu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-12-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506122003294 |
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