Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson’s disease

Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson’s disease

Abstract Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are progressive neurodegenerative diseases characterized by the accumulation of misfolded α-synuclein in the form of Lewy pathology. While most cases are sporadic, there are rare genetic mutations that cause disease and more commo...

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Bibliographic Details
Main Authors: Cheryl E. G. Leyns, Alice Prigent, Brenna Beezhold, Lihang Yao, Nathan G. Hatcher, Peining Tao, John Kang, EunRan Suh, Vivianna M. Van Deerlin, John Q. Trojanowski, Virginia M. Y. Lee, Matthew E. Kennedy, Matthew J. Fell, Michael X. Henderson
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-023-00517-w

Internet

https://doi.org/10.1038/s41531-023-00517-w

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