Alterations in White Matter Network and Microstructural Integrity Differentiate Parkinson’s Disease Patients and Healthy Subjects

Alterations in White Matter Network and Microstructural Integrity Differentiate Parkinson’s Disease Patients and Healthy Subjects

Parkinson’s disease (PD) is a neurodegenerative disease, neuropathologically characterized by progressive loss of neurons in distinct brain areas. We hypothesize that quantifiable network alterations are caused by neurodegeneration. The primary motivation of this study was to assess the specific net...

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Bibliographic Details
Main Authors: Nabin Koirala, Abdul Rauf Anwar, Dumitru Ciolac, Martin Glaser, Bogdan Pintea, Günther Deuschl, Muthuraman Muthuraman, Sergiu Groppa
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
diffusion MRI
network connectivity analysis
Parkinson’s disease
aging
white matter
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00191/full

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