ALKBH5 modulates macrophages polarization in tumor microenvironment of ovarian cancer

ALKBH5 modulates macrophages polarization in tumor microenvironment of ovarian cancer

Abstract Background Macrophages play an essential role in regulating ovarian cancer immune microenvironment. Studies have shown that m6A methylation could influence immune microenvironment in cancer. In this study, we investigated the roles of m6A demethylase ALKBH5 and m6A recognition protein IGF2B...

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Bibliographic Details
Main Authors: Yuanyuan An, Hua Duan
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
ALKBH5; IGF2BP2
Macrophage polarization
Immune microenvironment
Single-cell
Online Access:https://doi.org/10.1186/s13048-024-01394-4

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