Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease
In this work, we present the first steps toward the creation of a new neurorobotics model of Parkinson's Disease (PD) that embeds, for the first time in a real robot, a well-established computational model of PD. PD mostly affects the modulation of movement in humans. The number of people suffe...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-07-01
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| Series: | Frontiers in Neurorobotics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnbot.2021.640449/full |
| _version_ | 1819156946606882816 |
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| author | Jhielson M. Pimentel Renan C. Moioli Mariana F. P. de Araujo Caetano M. Ranieri Roseli A. F. Romero Frank Broz Patricia A. Vargas |
| author_facet | Jhielson M. Pimentel Renan C. Moioli Mariana F. P. de Araujo Caetano M. Ranieri Roseli A. F. Romero Frank Broz Patricia A. Vargas |
| author_sort | Jhielson M. Pimentel |
| collection | DOAJ |
| description | In this work, we present the first steps toward the creation of a new neurorobotics model of Parkinson's Disease (PD) that embeds, for the first time in a real robot, a well-established computational model of PD. PD mostly affects the modulation of movement in humans. The number of people suffering from this neurodegenerative disease is set to double in the next 15 years and there is still no cure. With the new model we were capable to further explore the dynamics of the disease using a humanoid robot. Results show that the embedded model under both conditions, healthy and parkinsonian, was capable of performing a simple behavioural task with different levels of motor disturbance. We believe that this neurorobotics model is a stepping stone to the development of more sophisticated models that could eventually test and inform new PD therapies and help to reduce and replace animals in research. |
| first_indexed | 2024-12-22T16:00:57Z |
| format | Article |
| id | doaj.art-ffe233789f5742ba822174a757945064 |
| institution | Directory Open Access Journal |
| issn | 1662-5218 |
| language | English |
| last_indexed | 2024-12-22T16:00:57Z |
| publishDate | 2021-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurorobotics |
| spelling | doaj.art-ffe233789f5742ba822174a7579450642022-12-21T18:20:41ZengFrontiers Media S.A.Frontiers in Neurorobotics1662-52182021-07-011510.3389/fnbot.2021.640449640449Neuro4PD: An Initial Neurorobotics Model of Parkinson's DiseaseJhielson M. Pimentel0Renan C. Moioli1Mariana F. P. de Araujo2Caetano M. Ranieri3Roseli A. F. Romero4Frank Broz5Patricia A. Vargas6Edinburgh Centre for Robotics, Heriot-Watt University, Edinburgh, United KingdomBioinformatics Multidisciplinary Environment, Digital Metropolis Institute, Federal University of Rio Grande do Norte, Natal, BrazilCCS, Federal University of Espírito Santo, Vitória, BrazilICMC, University of São Paulo, São Paulo, BrazilICMC, University of São Paulo, São Paulo, BrazilEdinburgh Centre for Robotics, Heriot-Watt University, Edinburgh, United KingdomEdinburgh Centre for Robotics, Heriot-Watt University, Edinburgh, United KingdomIn this work, we present the first steps toward the creation of a new neurorobotics model of Parkinson's Disease (PD) that embeds, for the first time in a real robot, a well-established computational model of PD. PD mostly affects the modulation of movement in humans. The number of people suffering from this neurodegenerative disease is set to double in the next 15 years and there is still no cure. With the new model we were capable to further explore the dynamics of the disease using a humanoid robot. Results show that the embedded model under both conditions, healthy and parkinsonian, was capable of performing a simple behavioural task with different levels of motor disturbance. We believe that this neurorobotics model is a stepping stone to the development of more sophisticated models that could eventually test and inform new PD therapies and help to reduce and replace animals in research.https://www.frontiersin.org/articles/10.3389/fnbot.2021.640449/fullneuroroboticsbasal gangliamotor controlParkinson's diseasemotor cortexrobot controller |
| spellingShingle | Jhielson M. Pimentel Renan C. Moioli Mariana F. P. de Araujo Caetano M. Ranieri Roseli A. F. Romero Frank Broz Patricia A. Vargas Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease Frontiers in Neurorobotics neurorobotics basal ganglia motor control Parkinson's disease motor cortex robot controller |
| title | Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease |
| title_full | Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease |
| title_fullStr | Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease |
| title_full_unstemmed | Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease |
| title_short | Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease |
| title_sort | neuro4pd an initial neurorobotics model of parkinson s disease |
| topic | neurorobotics basal ganglia motor control Parkinson's disease motor cortex robot controller |
| url | https://www.frontiersin.org/articles/10.3389/fnbot.2021.640449/full |
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