Autonomic dysfunction in chronic liver disease
James Frith, Julia L NewtonNIHR Biomedical Research Centre in Ageing, Institute for Ageing and Health, Newcastle University, Newcastle, UKAbstract: It is becoming increasingly clear that quality of life (QOL) is impaired in those with chronic liver disease (CLD). One of the most important contributo...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2011-08-01
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| Series: | Hepatic Medicine: Evidence and Research |
| Online Access: | http://www.dovepress.com/autonomic-dysfunction-in-chronic-liver-disease-a8128 |
| _version_ | 1818845151450103808 |
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| author | Frith J Newton JL |
| author_facet | Frith J Newton JL |
| author_sort | Frith J |
| collection | DOAJ |
| description | James Frith, Julia L NewtonNIHR Biomedical Research Centre in Ageing, Institute for Ageing and Health, Newcastle University, Newcastle, UKAbstract: It is becoming increasingly clear that quality of life (QOL) is impaired in those with chronic liver disease (CLD). One of the most important contributors to impaired QOL is the symptomatic burden which can range from slight to debilitating. Autonomic dysfunction accounts for a significant proportion of these symptoms, which can be common, non-specific and challenging to treat. Investigating the autonomic nervous system can be straight forward and can assist the clinician to diagnose and treat specific symptoms. Evidence-based treatment options for autonomic symptoms, specifically in CLD, can be lacking and must be extrapolated from other studies and expert opinion. For those with severely impaired quality of life, liver transplantation may offer an improvement; however, more research is needed to confirm this.Keywords: quality of life, treatment, fatigue, angiotensin II |
| first_indexed | 2024-12-19T05:25:06Z |
| format | Article |
| id | doaj.art-ffeba19974414435af7c17ccfbdae1ab |
| institution | Directory Open Access Journal |
| issn | 1179-1535 |
| language | English |
| last_indexed | 2024-12-19T05:25:06Z |
| publishDate | 2011-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Hepatic Medicine: Evidence and Research |
| spelling | doaj.art-ffeba19974414435af7c17ccfbdae1ab2022-12-21T20:34:24ZengDove Medical PressHepatic Medicine: Evidence and Research1179-15352011-08-012011default8187Autonomic dysfunction in chronic liver diseaseFrith JNewton JLJames Frith, Julia L NewtonNIHR Biomedical Research Centre in Ageing, Institute for Ageing and Health, Newcastle University, Newcastle, UKAbstract: It is becoming increasingly clear that quality of life (QOL) is impaired in those with chronic liver disease (CLD). One of the most important contributors to impaired QOL is the symptomatic burden which can range from slight to debilitating. Autonomic dysfunction accounts for a significant proportion of these symptoms, which can be common, non-specific and challenging to treat. Investigating the autonomic nervous system can be straight forward and can assist the clinician to diagnose and treat specific symptoms. Evidence-based treatment options for autonomic symptoms, specifically in CLD, can be lacking and must be extrapolated from other studies and expert opinion. For those with severely impaired quality of life, liver transplantation may offer an improvement; however, more research is needed to confirm this.Keywords: quality of life, treatment, fatigue, angiotensin IIhttp://www.dovepress.com/autonomic-dysfunction-in-chronic-liver-disease-a8128 |
| spellingShingle | Frith J Newton JL Autonomic dysfunction in chronic liver disease Hepatic Medicine: Evidence and Research |
| title | Autonomic dysfunction in chronic liver disease |
| title_full | Autonomic dysfunction in chronic liver disease |
| title_fullStr | Autonomic dysfunction in chronic liver disease |
| title_full_unstemmed | Autonomic dysfunction in chronic liver disease |
| title_short | Autonomic dysfunction in chronic liver disease |
| title_sort | autonomic dysfunction in chronic liver disease |
| url | http://www.dovepress.com/autonomic-dysfunction-in-chronic-liver-disease-a8128 |
| work_keys_str_mv | AT frithj autonomicdysfunctioninchronicliverdisease AT newtonjl autonomicdysfunctioninchronicliverdisease |