A case report of recurrent Well’s syndrome masquerading as cellulitis

Eosinophilic cellulitis (Well’s syndrome) is a rare relapsing inflammatory disorder characterized by infiltration of eosinophils into the dermis. Although rare, WS should be considered in patients with a history of asthma and skin lesions that are resistant to antibiotic therapy. We report a case of...

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Main Authors: Anum Qureshi, Jasmine Manley, Tristan Flack, Mark H. Lowitt
Format: Article
Language:English
Published: Greater Baltimore Medical Center 2021-11-01
Series:Journal of Community Hospital Internal Medicine Perspectives
Subjects:
Online Access:http://dx.doi.org/10.1080/20009666.2021.1979737
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author Anum Qureshi
Jasmine Manley
Tristan Flack
Mark H. Lowitt
author_facet Anum Qureshi
Jasmine Manley
Tristan Flack
Mark H. Lowitt
author_sort Anum Qureshi
collection DOAJ
description Eosinophilic cellulitis (Well’s syndrome) is a rare relapsing inflammatory disorder characterized by infiltration of eosinophils into the dermis. Although rare, WS should be considered in patients with a history of asthma and skin lesions that are resistant to antibiotic therapy. We report a case of recurrent WS. A 67-year-old woman with a history of asthma presented with a longstanding left pretibial ulcer with surrounding erythema, pain, and serous drainage, which had failed treatment with oral and parenteral antibiotics. Skin biopsy revealed eosinophilic cellulitis. Rapid improvement occurred with systemic steroid treatment; however, recurrent disease in the perineum developed as corticosteroids were tapered.
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spelling doaj.art-ffed2c7a9c064bf9ab5e0cad98ef02e22023-01-02T00:23:01ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662021-11-0111686687010.1080/20009666.2021.19797371979737A case report of recurrent Well’s syndrome masquerading as cellulitisAnum Qureshi0Jasmine Manley1Tristan Flack2Mark H. Lowitt3Greater Baltimore Medical CenterGreater Baltimore Medical CenterGreater Baltimore Medical CenterGreater Baltimore Medical CenterEosinophilic cellulitis (Well’s syndrome) is a rare relapsing inflammatory disorder characterized by infiltration of eosinophils into the dermis. Although rare, WS should be considered in patients with a history of asthma and skin lesions that are resistant to antibiotic therapy. We report a case of recurrent WS. A 67-year-old woman with a history of asthma presented with a longstanding left pretibial ulcer with surrounding erythema, pain, and serous drainage, which had failed treatment with oral and parenteral antibiotics. Skin biopsy revealed eosinophilic cellulitis. Rapid improvement occurred with systemic steroid treatment; however, recurrent disease in the perineum developed as corticosteroids were tapered.http://dx.doi.org/10.1080/20009666.2021.1979737well’s syndromeprednisonecellulitis
spellingShingle Anum Qureshi
Jasmine Manley
Tristan Flack
Mark H. Lowitt
A case report of recurrent Well’s syndrome masquerading as cellulitis
Journal of Community Hospital Internal Medicine Perspectives
well’s syndrome
prednisone
cellulitis
title A case report of recurrent Well’s syndrome masquerading as cellulitis
title_full A case report of recurrent Well’s syndrome masquerading as cellulitis
title_fullStr A case report of recurrent Well’s syndrome masquerading as cellulitis
title_full_unstemmed A case report of recurrent Well’s syndrome masquerading as cellulitis
title_short A case report of recurrent Well’s syndrome masquerading as cellulitis
title_sort case report of recurrent well s syndrome masquerading as cellulitis
topic well’s syndrome
prednisone
cellulitis
url http://dx.doi.org/10.1080/20009666.2021.1979737
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