Cocaine Use Disorder (CUD): Current Clinical Perspectives
Elizabeth KC Schwartz,1,2 Noah R Wolkowicz,1,2 Joao P De Aquino,1,2 R Ross MacLean,1,2 Mehmet Sofuoglu1,2 1Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; 2Department of Psychiatry, VA Connecticut Healthcare System, West Haven, CT, USACorrespondence: Elizabeth KC Sc...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2022-09-01
|
| Series: | Substance Abuse and Rehabilitation |
| Subjects: | |
| Online Access: | https://www.dovepress.com/cocaine-use-disorder-cud-current-clinical-perspectives-peer-reviewed-fulltext-article-SAR |
| _version_ | 1811277542556958720 |
|---|---|
| author | Schwartz EKC Wolkowicz NR De Aquino JP MacLean RR Sofuoglu M |
| author_facet | Schwartz EKC Wolkowicz NR De Aquino JP MacLean RR Sofuoglu M |
| author_sort | Schwartz EKC |
| collection | DOAJ |
| description | Elizabeth KC Schwartz,1,2 Noah R Wolkowicz,1,2 Joao P De Aquino,1,2 R Ross MacLean,1,2 Mehmet Sofuoglu1,2 1Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; 2Department of Psychiatry, VA Connecticut Healthcare System, West Haven, CT, USACorrespondence: Elizabeth KC Schwartz, Tel +1-203-932-5711, Fax +1-203-937-3472, Email Elizabeth.schwartz@yale.eduAbstract: Cocaine use disorder (CUD) is a devastating disorder, impacting both individuals and society. Individuals with CUD face many barriers in accessing treatment for CUD, and most individuals with CUD never receive treatment. In this review, we provide an overview of CUD, including risk factors for CUD, common co-occurring disorders, acute and chronic effects of cocaine use, and currently available pharmacological and behavioral treatments. There are no FDA-approved pharmacological treatments for CUD. Future studies with larger sample sizes and testing treatment combinations are warranted. However, individuals with CUD and co-occurring disorders (eg, a mood or anxiety disorder) may benefit from medication treatments. There are behavioral interventions that have demonstrated efficacy in treating CUD – contingency management (CM) and cognitive-behavioral therapy for substance use disorders (CBT-SUD) in particular – however many barriers remain in delivering these treatments to patients. Following the discussion of current treatments, we highlight some promising emerging treatments, as well as offer a framework that can be used in building a treatment plan for individuals with CUD.Keywords: cocaine, cocaine use disorder, treatment, pharmacotherapy, behavioral interventions |
| first_indexed | 2024-04-13T00:18:37Z |
| format | Article |
| id | doaj.art-fff219ef96124468b3003d19f0348a79 |
| institution | Directory Open Access Journal |
| issn | 1179-8467 |
| language | English |
| last_indexed | 2024-04-13T00:18:37Z |
| publishDate | 2022-09-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Substance Abuse and Rehabilitation |
| spelling | doaj.art-fff219ef96124468b3003d19f0348a792022-12-22T03:10:51ZengDove Medical PressSubstance Abuse and Rehabilitation1179-84672022-09-01Volume 13254677933Cocaine Use Disorder (CUD): Current Clinical PerspectivesSchwartz EKCWolkowicz NRDe Aquino JPMacLean RRSofuoglu MElizabeth KC Schwartz,1,2 Noah R Wolkowicz,1,2 Joao P De Aquino,1,2 R Ross MacLean,1,2 Mehmet Sofuoglu1,2 1Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; 2Department of Psychiatry, VA Connecticut Healthcare System, West Haven, CT, USACorrespondence: Elizabeth KC Schwartz, Tel +1-203-932-5711, Fax +1-203-937-3472, Email Elizabeth.schwartz@yale.eduAbstract: Cocaine use disorder (CUD) is a devastating disorder, impacting both individuals and society. Individuals with CUD face many barriers in accessing treatment for CUD, and most individuals with CUD never receive treatment. In this review, we provide an overview of CUD, including risk factors for CUD, common co-occurring disorders, acute and chronic effects of cocaine use, and currently available pharmacological and behavioral treatments. There are no FDA-approved pharmacological treatments for CUD. Future studies with larger sample sizes and testing treatment combinations are warranted. However, individuals with CUD and co-occurring disorders (eg, a mood or anxiety disorder) may benefit from medication treatments. There are behavioral interventions that have demonstrated efficacy in treating CUD – contingency management (CM) and cognitive-behavioral therapy for substance use disorders (CBT-SUD) in particular – however many barriers remain in delivering these treatments to patients. Following the discussion of current treatments, we highlight some promising emerging treatments, as well as offer a framework that can be used in building a treatment plan for individuals with CUD.Keywords: cocaine, cocaine use disorder, treatment, pharmacotherapy, behavioral interventionshttps://www.dovepress.com/cocaine-use-disorder-cud-current-clinical-perspectives-peer-reviewed-fulltext-article-SARcocainecocaine use disordertreatmentpharmacotherapybehavioral interventions |
| spellingShingle | Schwartz EKC Wolkowicz NR De Aquino JP MacLean RR Sofuoglu M Cocaine Use Disorder (CUD): Current Clinical Perspectives Substance Abuse and Rehabilitation cocaine cocaine use disorder treatment pharmacotherapy behavioral interventions |
| title | Cocaine Use Disorder (CUD): Current Clinical Perspectives |
| title_full | Cocaine Use Disorder (CUD): Current Clinical Perspectives |
| title_fullStr | Cocaine Use Disorder (CUD): Current Clinical Perspectives |
| title_full_unstemmed | Cocaine Use Disorder (CUD): Current Clinical Perspectives |
| title_short | Cocaine Use Disorder (CUD): Current Clinical Perspectives |
| title_sort | cocaine use disorder cud current clinical perspectives |
| topic | cocaine cocaine use disorder treatment pharmacotherapy behavioral interventions |
| url | https://www.dovepress.com/cocaine-use-disorder-cud-current-clinical-perspectives-peer-reviewed-fulltext-article-SAR |
| work_keys_str_mv | AT schwartzekc cocaineusedisordercudcurrentclinicalperspectives AT wolkowicznr cocaineusedisordercudcurrentclinicalperspectives AT deaquinojp cocaineusedisordercudcurrentclinicalperspectives AT macleanrr cocaineusedisordercudcurrentclinicalperspectives AT sofuoglum cocaineusedisordercudcurrentclinicalperspectives |