Antitumor Activity of Quinazolinone Alkaloids Inspired by Marine Natural Products
Many fungal quinazolinone metabolites, which contain the methyl-indole pyrazino [1,2-b]quinazoline-3,6-dione core, have been found to possess promising antitumor activity. The purpose of this work was to synthesize the enantiomeric pairs of two members of this quinazolinone family, to explore their...
Main Authors: | Solida Long, Diana I. S. P. Resende, Anake Kijjoa, Artur M. S. Silva, André Pina, Tamara Fernández-Marcelo, M. Helena Vasconcelos, Emília Sousa, Madalena M. M. Pinto |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-07-01
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Series: | Marine Drugs |
Subjects: | |
Online Access: | http://www.mdpi.com/1660-3397/16/8/261 |
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